Dead or Inactive Liver Mets!

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camicom
Posts: 40
Joined: Thu Jun 27, 2019 1:39 pm
Facebook Username: david galloway

Dead or Inactive Liver Mets!

Postby camicom » Mon Apr 13, 2020 11:39 am

Its been a pretty wild 7 days. After my scans earlier in the month showed a 40% decrease in tumor size(35 tumors) my Oncologist suggested that I wouldbe eligible for a liver resection. This gave me a lot of hope as it changes the 5 year survival rate from 11% to aound 50%. I talked to my liver sugeon on Friday and was disappointed to hear that I still wasn't eligible because of the lack of tumor free liver(about 15%). He did say that I was probably a candidate for what is called Y90 radioembolization, in which they send radioactive seeds into your liver tumors via femoral artery, and scheduled an appointment for me this morning with an Interventional Radiologist. After much research this seemed like a pretty good option.



I met the IR on Zoom this morning and was told I wasn't a candidate for the Y90, not because of my health or situation, but because my tumors are either dead or inactive. I asked him how did they know that, he said tumors on scans are lit up, and all of mine are not. He did say they could reactivate or go somewhere else but for now its great news. He said the Y90 would be useless because there is no active tumor for the Y90 to seed(if that makes sense)



Sorry for rambling. I acutally became emotional when he was telling me this. So the plan is continue chemo for now and scan again in about 6 weeks.



Life goes on my friends:)
6/17 Colonoscopy 5cm Malignant Neoplasm in Transverse Colon
CEA 1.2
Stage 3A
BRAF Neg
11/23 CT scan showed multiple Liver Mets
12/03 MRI showed 35 Liver mets largest being 2cm many very small Not resectable
12/10 CEA 4.5nl
12/11 Port Placement
12/12 Liver Biopsy confirming tumor same type as before
12/17 Started FolFox with Avastin
3/21 MRI Showed average 40% shrinkage and tumor inactive or dead
4/15 Started 4000mg daily of Xeloda as Maintenance
6/24 CT scan showed no growth, everything stable

boxhill
Posts: 789
Joined: Fri Apr 06, 2018 11:40 am

Re: Dead or Inactive Liver Mets!

Postby boxhill » Mon Apr 13, 2020 7:13 pm

Wow, that's quite a story!

I have had a very small liver thing, maybe 5mm, for at least the last year. It may be dead tissue, post Keytruda. No one knows. I haven't been able to get anyone to agree to remove it. It is too small to biopsy. For some reason no one has ever thought I should have a PET scan, which might show whether it was active (although I guess it is too small).

Very frustrating. I keep telling myself that it is better than having large and/or active liver mets.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 LN,5 mesentery nodes
5mm liver met
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/18 FOLFOX
7/18 and 11/18 CT NED
12/18 MRI 5mm liver mass, 2 LNs in porta hepatis
12/31/18 Keytruda
6/19 Multiphasic CT LNs normal, Liver stable
6/28/19 Pause Key, predisone for joint pain
7/31/19 Restart Key
9/19 CT stable
Pain: all fails but Celebrex
12/23/19 CT stable
5/20 MRI stable/NED
6/20 Stop Key
All MRIs NED


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