Postby plastikos » Thu Apr 16, 2020 8:43 am
Hi. I had SIRT/Y90 in October 2017 while I was on my first year of immunotherapy (Keytruda) to take care of a lesion that although PET negative was noted to have contrast uptake on CT (meaning it still had a blood supply). By that time that was the only lesion left unresponsive and all others had disappeared on almost half a year of treatment. I discussed it with my doctors and they agreed it was an low risk option for me.
There are 2 steps. The first is an hepatic artery angiogram to map out which area should receive treatment. They also consider the amount of liver that needs treatment. They discharge you after and schedule the actual radioembolization on a separate date.
Not much side effects except for abdominal discomfort, nausea, fatigue. They will monitor liver function after. Hope this helps.
St. IV Colon CA @ 37, male, Kras wild, MSI-high (2014)
11/2014 Right Hemicolectomy + Liver Resection
12/2014 - 6/2015 FOLFOX + Cetuximab
10/2015 - Recurrence liver
Liver resection 10/2015
FOLFIRI 11/2015 - 5/2016
Recurrence liver, nodes 11/2016
Pembrolizumab started 12/2016 -> pseudoprogression(?) -> biliary obstruction -> biliary stenting
Chemo 4x: most mets inactive and smaller on PET-CT
March 2017 - Back on Pembrolizumab again
Sept 2017 - SIRT - > NED
2019 NED