Liver lesions

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KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Liver lesions

Postby KarenE » Thu Mar 19, 2020 11:39 pm

Hello everyone. Haven't logged on for a couple of years but still visit often. Reaching out to get an opinion on latest ct scan please? Declared NED in 2018...clear scan and cea was 2 at last blood test 6 months ago. Usual simple cysts still visible and unchanged but new low density solid lesions have appeared which are deemed to be suspicious for metastatic deposits. G.P is arranging appointment with specialist. Does this mean a biopsy will be required to confirm? Many thanks forum friends, appreciate any advice.xxx
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

plastikos
Posts: 339
Joined: Wed Jan 14, 2015 6:09 am

Re: Liver lesions

Postby plastikos » Fri Mar 20, 2020 11:46 am

Hi Karen. I’m not an expert but I don’t think they would do a biopsy in this case. A PET scan or PET-CT might be the next step.
St. IV Colon CA @ 37, male, Kras wild, MSI-high (2014)
11/2014 Right Hemicolectomy + Liver Resection
12/2014 - 6/2015 FOLFOX + Cetuximab
10/2015 - Recurrence liver
Liver resection 10/2015
FOLFIRI 11/2015 - 5/2016
Recurrence liver, nodes 11/2016
Pembrolizumab started 12/2016 -> pseudoprogression(?) -> biliary obstruction -> biliary stenting
Chemo 4x: most mets inactive and smaller on PET-CT
March 2017 - Back on Pembrolizumab again
Sept 2017 - SIRT - > NED
2019 NED

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Fri Mar 20, 2020 4:52 pm

Thank you for the info. Just waiting now for an appointment to confirm one way or the other.
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

missb2020
Posts: 5
Joined: Wed Apr 15, 2020 9:24 am

Re: Liver lesions

Postby missb2020 » Wed Apr 15, 2020 10:11 am

Hi Karen just wanted to check and see if you had any updates?

My husband was diagnosed 4 years ago and all scans and CEA have been good since surgery and use of Capecitabine .

He went back to DR for 6 month check up today and they told him there was a spot on his liver that was not there 6 months ago and his CEA number jumped to 12 this time.

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Thu Apr 16, 2020 3:21 am

Hello, yes actually had an appointment today. 5 confirmed liver mets. An unrelated ultrasound detected suspicious lesions so ct scan followed. They were unsure if mets so then mri and pet scan to evaluate further. MDT meeting between liver surgeon, oncologist and specialist to decide on which path to take is happening on Monday. Hopefully after that we will have a plan. Bit of a shock that it has come back after 7 years but it is what it is. My cea has never been more than 2 since the day I was originally diagnosed so it isn't a good indicator for me. Best wishes to your husband too and hope all goes well.
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

missb2020
Posts: 5
Joined: Wed Apr 15, 2020 9:24 am

Re: Liver lesions

Postby missb2020 » Thu Apr 16, 2020 11:28 am

He went back today and there is a 2 inch mass on his liver. Do other spots. Doing a biopsy in the morning but DR is pretty sure it is cancer so going ahead and scheduling for a port to be put in and putting him in touch with a Specialist at Emory to see about surgery after Chemo.

We were almost at the 5 year mark. We both thought this was behind us. I hate this!

Praying for you and everyone going through this. Stay Strong.

User avatar
juliej
Posts: 3106
Joined: Thu Aug 05, 2010 12:59 pm

Re: Liver lesions

Postby juliej » Thu Apr 16, 2020 4:20 pm

KarenE wrote:Hello, yes actually had an appointment today. 5 confirmed liver mets. An unrelated ultrasound detected suspicious lesions so ct scan followed. They were unsure if mets so then mri and pet scan to evaluate further. MDT meeting between liver surgeon, oncologist and specialist to decide on which path to take is happening on Monday. Hopefully after that we will have a plan. Bit of a shock that it has come back after 7 years but it is what it is. My cea has never been more than 2 since the day I was originally diagnosed so it isn't a good indicator for me. Best wishes to your husband too and hope all goes well.

Karen, I see by your signature that you had two liver lesions at your original diagnosis in 2013. I am assuming they were resected at some point since you said you were declared NED in 2018??? If the resection was done in 2018, you are right in the statistical norm for a recurrence (2 years post-resection).

It sounds like you're one of the people for whom CEA is not a good indicator. Just curious if your oncologist has ever suggested a CA19-9 and/or an LDH test instead? They often work for a "heads up" for recurrences.

Hopefully, your docs will come up with a plan that will get you back to NED as soon as possible! Hang in there!

Juliej
Stage IVb, liver/lung mets 8/4/2010
Xelox+Avastin 8/18/10 to 10/21/2011
LAR, liver resec, HAI pump 11/2011
Adjuvant Irinotecan + FUDR
Double lung surgery + ileo reversal 2/2012
Adjuvant FUDR + Xeloda
VATS rt. lung 12/2012 - benign granuloma!
VATS left lung 11/2013
NED 11/22/13 to 12/18/2019, CEA<1

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Thu Apr 16, 2020 10:22 pm

Hi JulieJ, Original lesions were cysts and they are still there. Unfortunately there are new lesions which have only just shown on MRI and PET scans . Only ever had CT scans and bloods over the six years of monitoring. No chemo as I was stage 1. Surgery was ULAR in 2013. Three of the mets are small but other two are 2.6cm and 2.9cm. Not sure yet if any or all of them could be resected. Many thanks for your reply, much appreciated.
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Thu Apr 16, 2020 10:33 pm

Missb2020 , sorry to hear that your husband is dealing with this too. Just when we think we are out of the woods we are thrown a curve ball. All the best to you and your husband. Take care.
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Thu Apr 16, 2020 10:35 pm

My apologies for the late responses but I live in Australia .Thank you everyone.xx
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Wed May 20, 2020 4:11 am

Just updating previous post. Liver resection booked in for Monday 25th. Only 3 tumours can be resected other 2 will have microwave ablation. Not looking forward to it but grateful that it can be done. Chemo will start 4 weeks after surgery. Best wishes to everyone.xx
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

boxhill
Posts: 554
Joined: Fri Apr 06, 2018 11:40 am

Re: Liver lesions

Postby boxhill » Wed May 20, 2020 6:47 pm

Excellent news that they will treat all of them aggressively! I hope all goes smoothly and your recovery is rapid and uneventful.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 nodes,5 mesentery nodes
5mm liver met out
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/18 FOLFOX
7/18 CT NED
11/18 CT NED
12/18 MRI 5mm liver mass, 2 lymph nodes in porta hepatis
12/31/18 Keytruda
6/19 Multiphasic CT LNs normal, Liver stable
6/28/19 Pause Key, predisone for joint pain
7/31/19 Restart Key
9/19 CT stable
Pain: all fails but Celebrex
12/23/19 CT stable
5/19 MRI stable/NED
Suspend treatment

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Thu May 21, 2020 12:41 am

Thank you Boxhill for the good wishes. xxx
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.

kandj
Posts: 293
Joined: Sun Sep 27, 2015 11:29 am

Re: Liver lesions

Postby kandj » Thu May 28, 2020 6:13 pm

Karen, I hope your surgeries went well and were uneventful. I’m sorry you are having to do all of this during the Covid Crisis. :(
wife to DH, dx 8/15 stage IV @36, numerous unresectable liver Mets
resection and HAI placed 12/15
Liver resection 5/19/2016 15-20 mets removed (surgeon lost count, but it hopeful he got it all!)
Recurrence 7/2017 4 Liver mets and one possible lung met
Radiation on liver Mets 12/17
Lung met 10/18
VATS on lung met 11/18 started xeloda
Chemo break 6/19-11/19 lung/adrenal gland recurrence 11/19
Adrenal ablation2/20 Robotic Assisted VATS 3/20 Xeloda again

KarenE
Posts: 17
Joined: Sun Feb 14, 2016 1:56 am

Re: Liver lesions

Postby KarenE » Tue Jun 16, 2020 7:30 pm

Update...liver resection was scheduled for May 25th. Three larger tumours to be removed and the other two would be microwave ablated. All didn't go to plan as none could be resected after all so were ablated instead. Healing well...ribs hurt more than wound. Scan in a week or so and when surgical site no longer needs packing and dressing by community nurse, chemo can start. Good to know that plans are in place. Take care everyone...comforting to visit this lovely group.xxxx
DX March 2013 rectal cancer,T1NOMX 0/15 nodes,lymphovascular invasion present/moderate, 2 liver lesions, 1 lesion spleen probable cysts. Parastomal hernia. Latest scan shows change/ bowel wall thickening at anastomosis site.


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