Any one experience with pelvis, perirectal and lung met

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Suniva
Posts: 15
Joined: Mon Sep 30, 2019 4:03 pm

Any one experience with pelvis, perirectal and lung met

Postby Suniva » Mon Mar 16, 2020 3:07 pm

Hi all,

Last scan showed the tumor are increasing in size at peritoneal and perirectal, also new nodules are seen at right lung and increasing at left lung. Any one has same issue like this and if yes what chemo are you taking on this, however I am allergy to Oxi and xeloda is not working for me. I am wondering which chemo can be used, doc told that he can use folfixi. I am very much worried, is this be treatable condition or not. Can you please share your experiences?
DT 41yrs 10/18 on 3C, and small nod r/l lungs
11 lap surg
12/1805/2019 CAPOX total 8cyc (inc and dec tumor)
09 thoracotomy at right lung took two nodules, still left at left lung.metastatic to lung
10-Started CAPOX again
10/31/19-2nd cycle Allergic to OX taking CAP oral chemo alone for 1 cycle, CT scan showed left nodule inc. from 5to6mm
12/19 ct scan ndoc visit 7mm. Doc want to do 3 cycles of CAP
2/18 pet n ultrasound endo confirmed metastatic to perirectal 4mm
3/16 CT new nods at r/l lungs, inc pelvis

Claudine
Posts: 386
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Any one experience with pelvis, perirectal and lung met

Postby Claudine » Mon Mar 16, 2020 3:36 pm

I'm sorry this is happening Suniva... My husband did Folfiri + Avastin and that seemed to take care of his lung nodules. Like you he's refractory to Oxaliplatin. Folfiri is a good choice for second-line chemo!
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT 04/18, SBRT 02/19
Resect small intestine 05/18 (no cancer - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin 03/19 to 01/20
6.7 cm left adrenal mass 03/19, successful resection 02/20
CEA since 03/19: high 58, low 3.2, now 4.4
Scan 03/19: Multiple small lung nodules up to 5mm
Scan 12/19: one 1mm stable nodule
PET 04/20 uptake by L4
L3-L4-L5 fusion surgery and residual tumor removal 05/20

Gloriamazz
Posts: 70
Joined: Thu Jul 12, 2018 1:59 pm
Facebook Username: gloriamazz@ yahoo.com
Location: Ohio
Contact:

Re: Any one experience with pelvis, perirectal and lung met

Postby Gloriamazz » Mon Mar 16, 2020 8:31 pm

Hi,
I had everything you mention The perineal was taken care of during surgery and the lung Mets given irinotecan and fu-5 was on oxaliplatin.

I was allergic to oxaliplatn while on it nodules didn’t grow but they didn’t shrink. Although for 3 weeks not given oxaliplatin. Just given fu5 and grew up to two centimeters

Waiting for April for ct scan. Now taking nothing have to have gallblader removed go tomorrow surgeon on Wed fid out when operation
June 29, 2018 Colonoscopy
3cm leision adenocarcinoma
Operated August 8, 2018 Had APR removed Anus, Rectum,Sigmoid Colon
Barbie Butt permanent Colostomy
March 5, 2019. CT 2 lung nodules repeat CT 6 MonthSept. 10,
April 29, 2019 HyperDense Liesion 1.8 x 1.8 cm
July 22 2019; Monday 1 radiation painful dense Pelvis tumor 4-29-2019 ( more tired than usual) total of 5 radiations tumor is a recurrence of original colon cancer plus met to lungs
July 24, 2019 Wednesday 2nd radiation treament.

Suniva
Posts: 15
Joined: Mon Sep 30, 2019 4:03 pm

Re: Any one experience with pelvis, perirectal and lung met

Postby Suniva » Mon Mar 23, 2020 5:01 pm

Thank you for reply, my husband started his treatment again with Folfiri + cetuximab, provided cetuximab, Irinotecan + leucovorin as infusion and 5FU for 46 hrs taken at home by pump.

While taking chemo did you face any tireness, or fatigue. like my husband just laid down and close his eyes after his infusion, like he got it on last friday march 20, and he is sleepy, feeling tired and laying on the bed. Though he was very active person during recovery period from surgery also he used to move actively here and there. But after this first cycle it make his very tired and weak. Do you any feel same while on that chemo?
Thank you
Suniva
DT 41yrs 10/18 on 3C, and small nod r/l lungs
11 lap surg
12/1805/2019 CAPOX total 8cyc (inc and dec tumor)
09 thoracotomy at right lung took two nodules, still left at left lung.metastatic to lung
10-Started CAPOX again
10/31/19-2nd cycle Allergic to OX taking CAP oral chemo alone for 1 cycle, CT scan showed left nodule inc. from 5to6mm
12/19 ct scan ndoc visit 7mm. Doc want to do 3 cycles of CAP
2/18 pet n ultrasound endo confirmed metastatic to perirectal 4mm
3/16 CT new nods at r/l lungs, inc pelvis

boxhill
Posts: 557
Joined: Fri Apr 06, 2018 11:40 am

Re: Any one experience with pelvis, perirectal and lung met

Postby boxhill » Tue Mar 24, 2020 5:04 pm

Although I've never been on Folfiri, I, like just about everyone else, had intense cyclical fatigue while on Folfox. Eventually, around round 8, the fatigue seemed to be more general.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 nodes,5 mesentery nodes
5mm liver met out
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/18 FOLFOX
7/18 CT NED
11/18 CT NED
12/18 MRI 5mm liver mass, 2 lymph nodes in porta hepatis
12/31/18 Keytruda
6/19 Multiphasic CT LNs normal, Liver stable
6/28/19 Pause Key, predisone for joint pain
7/31/19 Restart Key
9/19 CT stable
Pain: all fails but Celebrex
12/23/19 CT stable
5/19 MRI stable/NED
Suspend treatment


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