I don’t often make definitive statements here but I think the short answer is no, it isn’t anything to worry about. 1 is a very low CEA; probably lower than many of the population without cancer. A single increase of 0.3 is not consequential by itself. I believe one guideline is to investigate 3 increases in a row; and/or any increase that takes it above 5.0.
Also, CEA whilst on chemo can jump around as well due to the treatment effects.
Congrats on almost finishing chemo!
10/2018 Dx 3.5cm RC adenocarcinoma, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1
11/18 FOLFOX x6
3/19 Liver resect
5/19 25x pelvic VMAT radiation; complete met. response
07/19 Robot ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resect #2
02/20 Ileo reversed
03/20 NED (PET+MRI)
06/20 NED (CT+MRI)
07/20 Clear scope