NCT03981614: Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic

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tbt4snow
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Joined: Sat Oct 27, 2018 3:16 pm
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NCT03981614: Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic

Postby tbt4snow » Mon Jan 20, 2020 4:35 pm

Hello,
Has anyone participated in this trial? https://clinicaltrials.gov/ct2/show/NCT ... w=2&rank=1
If you do, how are the side effects and if it has been working for you?
Any feedback is greatly appreciated.
Tina.
DX: CC stage 4/w ovaries & omentum mets in 12/17 49/F
High grade pT3N1bM1b sigmoid Adenocarcinoma colon
MSS-h TMB=16, NRAS-mutant
Lymph nodes: 1/2 left colic; 3/8 regional
12/2017: Exploratory laparotomy & resect of sigmoid & ovaries
Folfox/avastin 12 sessions from 1/8-6/18. 6/18 CEA 2.1
1/19: CT shows peri mets;
CEA: 12/18 5.1, 1/7/19 7.9; 1/15/19 9.1; 1/30/19: 10.6
4/3/2019 CRS/HIPEC after 4 Folfiry sessions...

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