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2020 Immunotherapy updates

Posted: Sun Jul 12, 2020 1:09 pm
by CRguy

Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer

Posted: Wed Jul 22, 2020 2:26 pm
by CRguy
TAKE-HOME MESSAGE

The authors of this post hoc analysis of a randomized phase III trial evaluated the impact of treatment adherence to neoadjuvant chemoradiotherapy and/or adjuvant chemotherapy on disease-free survival among 1232 patients with locally advanced rectal cancer. Complete adherence to neoadjuvant chemoradiotherapy compared with reduced adherence was associated with improved 3-year disease-free survival. However, complete versus incomplete adherence to adjuvant chemotherapy was not associated with disease-free survival.

Future trials should be designed to facilitate the delivery of optimal neoadjuvant chemoradiotherapy.

– Paul J. Hampel, MD


Association of Treatment Adherence With Oncologic Outcomes for Patients With Rectal Cancer

Medications to Treat High Blood Pressure May Reduce Risk of Colorectal Cancer

Posted: Fri Aug 28, 2020 10:45 am
by Beckster
A recent study found a 22% lower risk in developing colorectal cancer in the 3 years after patients took hypertension medications to treat high blood pressure, heart failure, or heart disease.
https://www.cancernetwork.com/view/medi ... FpbC5jb20=

Study Suggests PDE5 Inhibitors May Have Anti-Cancer Potential in Male Patients with CRC

Posted: Wed Oct 07, 2020 1:20 pm
by Beckster
Researchers suggested that potency enhancing phosphodiesterase-5 inhibitor drugs may have the ability to improve a prognosis in patients with colorectal cancer.
A study published in Nature Communications suggested that potency enhancing phosphodiesterase-5 (PDE5) inhibitor drugs, such as sildenafil (Viagra), have an anti-cancer potential with the ability to improve a prognosis in patients with colorectal cancer (CRC).


https://www.cancernetwork.com/view/stud ... FpbC5jb20=

Scientists discovered that your outcome is better when you deal with a good rather than with a bad surgeon

Posted: Sun Nov 01, 2020 2:49 pm
by Utwo

Re: ***News Stories Thread*** ONGOING 2020

Posted: Sun Nov 15, 2020 1:17 am
by Maggie Nell
Be the change you want to see in the world........

https://www.abc.net.au/news/2020-11-15/ ... s/12876648

A statement of claim on behalf of Mr Whitehead has been lodged, alleging his treatment from both the Maryborough District Health Service and his former GP were negligent.

The document, lodged with the court in October, argues the alleged negligence had resulted in "injury, loss and damage", including the "progression of caecal adenocarcinoma, metastatic spread of adenocarcinoma, and reduced life expectancy".

"There is a difference between unlucky, and perhaps negligent, circumstances," Mr Whitehead's lawyer, Alice Robinson, said.



https://www.abc.net.au/news/2018-02-04/ ... er/9371386

Jodie Elisara first began suffering painful symptoms of bowel cancer in 2009, but another eight years would pass before doctors diagnosed the disease and began to treat it.


Ms Elisara, 36, said she noticed rectal bleeding, low iron levels and had extreme pain when passing stools, but her doctor told her it was haemorrhoids.

After multiple visits to three different GPs over the following years, the pain became unbearable.

"I went back to the doctors and said: 'You need to do something, even if it is haemorrhoids I want something done, I can't continue living like this'," she said.

Ms Elisara said she was eventually referred for a colonoscopy [...] in May 2015 but waited months on a list before having surgery for haemorrhoids in January 2017.

"That's when he [the doctor] told me that I actually had no haemorrhoids at all but I had a very large tumour in my colon," she said.

She was diagnosed with stage 3 bowel cancer.

"This case really stands out as an example of a young person really trying to do the right thing, but who has been terribly let down by the medical profession," Ms Atkinson said.

Re: ***News Stories Thread*** ONGOING 2020

Posted: Sun Nov 15, 2020 4:50 am
by I_will_fight
Maggie Nell wrote:Be the change you want to see in the world........

https://www.abc.net.au/news/2020-11-15/ ... s/12876648

A statement of claim on behalf of Mr Whitehead has been lodged, alleging his treatment from both the Maryborough District Health Service and his former GP were negligent.

The document, lodged with the court in October, argues the alleged negligence had resulted in "injury, loss and damage", including the "progression of caecal adenocarcinoma, metastatic spread of adenocarcinoma, and reduced life expectancy".

"There is a difference between unlucky, and perhaps negligent, circumstances," Mr Whitehead's lawyer, Alice Robinson, said.



https://www.abc.net.au/news/2018-02-04/ ... er/9371386

Jodie Elisara first began suffering painful symptoms of bowel cancer in 2009, but another eight years would pass before doctors diagnosed the disease and began to treat it.


Ms Elisara, 36, said she noticed rectal bleeding, low iron levels and had extreme pain when passing stools, but her doctor told her it was haemorrhoids.

After multiple visits to three different GPs over the following years, the pain became unbearable.

"I went back to the doctors and said: 'You need to do something, even if it is haemorrhoids I want something done, I can't continue living like this'," she said.

Ms Elisara said she was eventually referred for a colonoscopy [...] in May 2015 but waited months on a list before having surgery for haemorrhoids in January 2017.

"That's when he [the doctor] told me that I actually had no haemorrhoids at all but I had a very large tumour in my colon," she said.

She was diagnosed with stage 3 bowel cancer.

"This case really stands out as an example of a young person really trying to do the right thing, but who has been terribly let down by the medical profession," Ms Atkinson said.



Thanks for this. This is something to keep in mind.

Sorry to digress, but I have one question regarding your signature, why is Sorbitol the devil? Is this CRC related or just general devility?

Re: ***News Stories Thread*** ONGOING 2020

Posted: Sun Nov 15, 2020 1:00 pm
by Maggie Nell
:mrgreen: