The authors of this post hoc analysis of a randomized phase III trial evaluated the impact of treatment adherence to neoadjuvant chemoradiotherapy and/or adjuvant chemotherapy on disease-free survival among 1232 patients with locally advanced rectal cancer. Complete adherence to neoadjuvant chemoradiotherapy compared with reduced adherence was associated with improved 3-year disease-free survival. However, complete versus incomplete adherence to adjuvant chemotherapy was not associated with disease-free survival.
Future trials should be designed to facilitate the delivery of optimal neoadjuvant chemoradiotherapy.
– Paul J. Hampel, MD
https://www.cancernetwork.com/view/medi ... FpbC5jb20=A recent study found a 22% lower risk in developing colorectal cancer in the 3 years after patients took hypertension medications to treat high blood pressure, heart failure, or heart disease.
Researchers suggested that potency enhancing phosphodiesterase-5 inhibitor drugs may have the ability to improve a prognosis in patients with colorectal cancer.
A study published in Nature Communications suggested that potency enhancing phosphodiesterase-5 (PDE5) inhibitor drugs, such as sildenafil (Viagra), have an anti-cancer potential with the ability to improve a prognosis in patients with colorectal cancer (CRC).
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