Regorafenib and Pembrolizumab

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meatie
Posts: 419
Joined: Wed Aug 20, 2014 8:13 am
Location: San Jose, CA

Regorafenib and Pembrolizumab

Postby meatie » Mon Dec 30, 2019 4:43 pm

Hi,
Is there any clinical trials /data on the use of Regorafenib and Pembrolizumab together on colon cancer patients?

meatie
Mother DX @59 8/14
cln+lvr res 9/14, stage 4
FOLOX+Avs 12-rd 10/14 to 4/15
Reoccurrence, KRAS mutant 11/15
Folfiri 18-rds 11/15-8/16
FOLFIRI with Ramicirumab 28-rds 8/17-9/18
Regorafenib 10/18-10/19
Lonsurf 10/19 onward
Folfox rechallenge 05/20
Regonivo (Opdivo+Stivarga) 08/20
External Peace 09/12/2022

claudine
Posts: 809
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Regorafenib and Pembrolizumab

Postby claudine » Mon Dec 30, 2019 5:06 pm

Hi meatie,
I did a quick google search and this one popped up:

https://clinicaltrials.gov/ct2/show/NCT03657641
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A, no primary

Tumors: L4 04/18; left adrenal gland & small lung nodules 03/19
rectum 02/22 (pT3 pN0 stage 2A); L3 09/22

Surgeries: intestinal resect. 05/18 (no cancer - Crohn's); adrenalectomy 02/20
L3-L4-L5 fusion and corpectomy 05/20; LAR 04/22; ileo reversal 09/22
L2-L3 fusion and corpectomy 09/22

Treatments: EBRT 04/18; SBRT 02/19; Failed adjuvant Xelox ; Folfiri/Avastin 03/19 - 01/20
adjuvant chemorad (Xeloda) 06/22; SBRT 11/22; Xeloda/Avastin since 01/24


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