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Pill thru j tube

Posted: Thu Dec 05, 2019 11:27 pm
by natelaugh
I need help. My dad has a cancer blockage at the duodenum. He got his GJ tube to bypass the blockage and it is working. He needs to get encorafenib and binimetinib but it is in pill form and he can't take by mouth. The Kaiser pharmacy don't have a safe way to give my dad encorrafenib and binimetinib thru his j tube. They say there is no study or any information on how to do it.

1,) Do anyone know a study or a method that Kaiser pharmacy can do it?

2.) Can radiation work on v600e mutation? We are thinking to use radiation to shrink the tumor so there is enough room to take the pill thru mouth.

Please give some feedback. Thx.

Re: Pill thru j tube

Posted: Fri Dec 06, 2019 8:46 am
by martd
Any possibility of dissolving the pill in a small amount of water and taking it in liquid form?

Re: Pill thru j tube

Posted: Fri Dec 06, 2019 9:43 am
by natelaugh
martd wrote:Any possibility of dissolving the pill in a small amount of water and taking it in liquid form?

Hi,

Kaiser pharmacy say it has not been done before and don't know a safe way of doing it. I thought if pill can be crush in small particles then mix in water and feed it thru j tube.

Nate.

Re: Pill thru j tube

Posted: Fri Dec 06, 2019 10:39 am
by martd
Most likely it's beyond the pharmacy to make that call. Have you discussed it with the doctors? They might ok with it or feel it's safe enough to try.

Re: Pill thru j tube

Posted: Fri Dec 06, 2019 11:04 am
by KimT
I am a nurse and this is based on my own experience. Pills are meant to be digested in the stomach and absorbed in the intestines. When you crush them, it can change the absorption rate and efficacy. Some pills cannot be crushed at all. You have the added issue of a j tube. The problem with putting things in a j tube is that it passes the stomach completely and digestion. That also can change the efficacy and absorption. The stomach is where it gets broken down into a state where it can be absorbed.

In my opinion, pharmacists are more knowledgeable about drugs in general. They are definitely more knowledgeable about interactions and absorption rates etc. The buck stops with the pharmacist in my experience and if they say it cannot be done, that is likely the case.