wife2jeff wrote: ..... has anyone on here ever stop oxy and do just 5fu for stage 3? He is just not tolerating it well, they have him on 3 different nausea meds plus they gave him 3 as premeds. Any help advise your experience would be great. thanks
Baaaaack in the day ..... infused 5FU/leucovorin was the major option, then oxaliplatin was added/recommended
for a 3-5% benefit.
Originally thought to be a Stage 3C, I chose Xeloda (basically oral 5FU with benefits ) for neoadjuvant chemoradiation and adjuvant chemo post resection. The Onc actually seemed to be not very enthusiastic about adding Oxy so I didn't.
About 3 years later with the lung met discovery I went "all in" with the FOLFOX regime and did 12 cycles with a dose reduction of Oxy around cycle 8. Tomorrow actually, I am going in for a recheck EMG to follow up on neuropathy issues ( mild ) which my Docs want to keep an eye on.
Most folks don't want to do 12 FULL Oxy cycles.
Most do not tolerate it well.
LESS cycles are being validated as not inferior to MORE cycles.
IF it is kicking his ass ... YES I would seriously talk to docs about dropping it if dose reductions are not making things better.
I never had major nausea issues, so I toughed it out.
I am 9 years out from my last dose of evil Oxy / Satan in a Bag
Did it help me to be here now ? Did I get a met because I didn't have it at resection ?
Truth is I don't really know.
IF I had the issues your hubby is having ... Yes I would have dumped it,
looked for alternatives and engage in VERY aggressive follow up monitoring ( which I did anyway !!!)
...AND Yes, my friend ... No it is not your decision
Support him, give him all the info we have here.
My B-I-L had a similar rectal tumor to mine, same surgeon, same oncologist.
ONLY had 5FU at the time ( 5 years prior to me and 6 years younger at the time )
He had no recurrences / I had ONE !
You tell me which is the best scenario ????
Every patient is different, and so is every outcome,
so if the treatment is worse than the disease ..... ?
We can only DO what we can do.
Quality over quantity is what I would chose
Cheers and best wishes to you and hubby.
on the Journey with y'all