Nikan1 wrote:Hi ,
I understand your stress very well, when my mother’s CEA spiked to 40 just three months after finishing chemo, your post saved me from nervous breakdown ! Now I hope I can help you to calm down.my mom was diagnosed with stage 3b rectal cancer(recto sigmoid junction ) in July 2017.After first spike in CEA she had a full CT scan with contrast,it was clear, in two weeks her CEA jumped to 73, then to 90 !!!! A pet scan ,endoscopy and colonoscopy was ordered, nothing was found.She had all kind of possible blood works to find a reason, again nothing was found.It came down little by little during a one year period, without any treatment.for last two months it is stable at 1.9,so your significant spike can be a false positive too.
When cancer was found ,her CEA level was 1.8.Doctor said CEA is not a good marker for her, now after all that happened I don’t know what to think.
radnyc wrote:The search is on for a superior testing method based on individual tumor DNA, which is the way to go. I found this quote from Dr. Axel Grothey, a well known oncologist at the Mayo Clinic:
“ Dr. Grothey says he considers CEA to be a valuable surveillance test, but that research into better tests is ongoing. “The future of ‘tumor markers' lies in the determination of circulating tumor DNA, preferably based on a mutational analysis of the resected primary tumor to follow patients with this highly sensitive technology to see if they have evidence of minimal residual disease,” he says.”
Amarie123 wrote:CEA can apparently spike for a number of non cancer related reasons. A friend of mine has been cancer free for 7 years but her CEA was always up and down. She has some lung infections due to damage from radiation, which her docs at Dana Farber think could be the cause. They have stopped monitoring her CEA because of this and instead use other bloodwork as a marker (I don’t know what tests they use).
In my experience, the only significant jump in CEA I had was immediately after radiation. With my original tumor and the new ones, my CEA remains in the normal/low normal range. It’s not a good marker for many people.
zx10guy wrote:We may end up ceasing to monitor CEA.
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