When we got the results of my husband's analysis, I jumped on Google hoping I'd read something like, "Stage 4 CRC is really really bad UNLESS you have a KRAS G12A mutation, in which case there's a miracle drug that will heal you!". Well maybe not exactly like that, but you get my drift.
As you can imagine, that's not the case. I think studies that state that one mutation is "worse" than another can be misleading; they're often based on small sample sizes, and older data. Cancer in general is pretty bad news, but as you can see from survivors who post here, it's not the death sentence that it used to be!
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT radiation 04/18, SBRT 02/19
Resection small intestine 05/18 (no cancer found - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin since 03/19
6.7 cm left adrenal mass 03/19, 3.67 cm 12/19, surgery scheduled for 02/11
CEA since 03/19: high 58, low 3.2, now 10.2
Scan 03/19: Multiple small lung nodules up to 5mm
Scan 12/19: 2 calcified granulomas, one 1mm stable nodule