A ‘standard’ full course of oxaliplatin is 12 cycles (24 weeks), but in trials typically around 80% of patients don’t make it this far - needing either a dose reduction or to change treatments due to side effects.
I did 6 cycles then had some delayed-onset neuropathy which almost fully resolved; I then did 3 more cycles and stopped due to an allergic reaction.
Indeed as Rich says there were some past studies suggesting that supplementing glutamine and calcium may be protective against neuropathy. I believe more recent research has suggested this may not be helpful however. There is also some weak suggestion that additional glutamine intake may promote tumour proliferation, so for this reason alone I’ve avoided it.
10/2018 Dx 3.5cm RC adenocarcinoma, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1
11/18 FOLFOX x6
3/19 Liver resect
5/19 25x pelvic VMAT radiation; complete met. response
07/19 Robot ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resect #2
02/20 Ileo reversed
03/20 NED (PET+MRI)
06/20 NED (CT+MRI)
07/20 Clear scope