Colon tumor metastasis to pelvis

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Gloriamazz
Posts: 70
Joined: Thu Jul 12, 2018 1:59 pm
Facebook Username: gloriamazz@ yahoo.com
Location: Ohio
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Colon tumor metastasis to pelvis

Postby Gloriamazz » Mon Sep 23, 2019 8:26 pm

Hi,

Is it unusual for metastatic Tumor not to shrink after after 5 chemo treatments
June 29, 2018 Colonoscopy
3cm leision adenocarcinoma
Operated August 8, 2018 Had APR removed Anus, Rectum,Sigmoid Colon
Barbie Butt permanent Colostomy
March 5, 2019. CT 2 lung nodules repeat CT 6 MonthSept. 10,
April 29, 2019 HyperDense Liesion 1.8 x 1.8 cm
July 22 2019; Monday 1 radiation painful dense Pelvis tumor 4-29-2019 ( more tired than usual) total of 5 radiations tumor is a recurrence of original colon cancer plus met to lungs
July 24, 2019 Wednesday 2nd radiation treament.

Rock_Robster
Posts: 507
Joined: Thu Oct 25, 2018 5:27 am
Location: Melbourne, Australia

Re: Colon tumor metastasis to pelvis

Postby Rock_Robster » Mon Sep 23, 2019 8:47 pm

Gloriamazz wrote:Hi,

Is it unusual for metastatic Tumor not to shrink after after 5 chemo treatments

Hi Gloriamazz, just to clarify - where is the the tumour you’re referring to located?
38M Australia
10/2018 Dx 3.5cm RC adenocarcinoma, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1
11/18 FOLFOX x6
3/19 Liver resect
5/19 25x pelvic VMAT radiation; complete met. response
07/19 Robot ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resect #2
02/20 Ileo reversed
03/20 NED (PET+MRI)
06/20 NED (CT+MRI)
07/20 Clear scope

Gloriamazz
Posts: 70
Joined: Thu Jul 12, 2018 1:59 pm
Facebook Username: gloriamazz@ yahoo.com
Location: Ohio
Contact:

Re: Colon tumor metastasis to pelvis

Postby Gloriamazz » Mon Sep 23, 2019 11:51 pm

Hi

The tumor is an enlarging hypodense lesion in the left hemi pelvis differential diagnosis the left hemi pelvis posteriorly just medial to the post acetubulum,there is a 1.8 x 1.87 cm hypertensive lesion which previously measured 1.5

It didn’t grow but it didn’t shrink.

Thank you
June 29, 2018 Colonoscopy
3cm leision adenocarcinoma
Operated August 8, 2018 Had APR removed Anus, Rectum,Sigmoid Colon
Barbie Butt permanent Colostomy
March 5, 2019. CT 2 lung nodules repeat CT 6 MonthSept. 10,
April 29, 2019 HyperDense Liesion 1.8 x 1.8 cm
July 22 2019; Monday 1 radiation painful dense Pelvis tumor 4-29-2019 ( more tired than usual) total of 5 radiations tumor is a recurrence of original colon cancer plus met to lungs
July 24, 2019 Wednesday 2nd radiation treament.

Gloriamazz
Posts: 70
Joined: Thu Jul 12, 2018 1:59 pm
Facebook Username: gloriamazz@ yahoo.com
Location: Ohio
Contact:

Re: Colon tumor metastasis to pelvis

Postby Gloriamazz » Mon Sep 23, 2019 11:53 pm

I also had 5 treatments of pelvis radiation
June 29, 2018 Colonoscopy
3cm leision adenocarcinoma
Operated August 8, 2018 Had APR removed Anus, Rectum,Sigmoid Colon
Barbie Butt permanent Colostomy
March 5, 2019. CT 2 lung nodules repeat CT 6 MonthSept. 10,
April 29, 2019 HyperDense Liesion 1.8 x 1.8 cm
July 22 2019; Monday 1 radiation painful dense Pelvis tumor 4-29-2019 ( more tired than usual) total of 5 radiations tumor is a recurrence of original colon cancer plus met to lungs
July 24, 2019 Wednesday 2nd radiation treament.

Rock_Robster
Posts: 507
Joined: Thu Oct 25, 2018 5:27 am
Location: Melbourne, Australia

Re: Colon tumor metastasis to pelvis

Postby Rock_Robster » Tue Sep 24, 2019 1:16 am

Ok thanks gloriamazz. So from this description it sounds like the lesion is in the pelvic bone itself - is this correct? If this is the case then it may not respond to chemo as well as an organ with very good blood supply might, though radiation might normally be more effective. Perhaps others will have had some experience with this that they can help you with.

Have you had a PET scan either before or after treatment to confirm the metabolic activity level of the lesion?
38M Australia
10/2018 Dx 3.5cm RC adenocarcinoma, 12cm high
Mod diff, EMVI+ LVI+. 4 liver mets
pT3N1aM1a Stage IVa. MSS NRAS G13R
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0, Mar-20=2.2, May-20=1.9, Jun-20=2.1
11/18 FOLFOX x6
3/19 Liver resect
5/19 25x pelvic VMAT radiation; complete met. response
07/19 Robot ULAR w ileo, 1/27 LN+
08/19 Found liver spot
08/19 FOLFOX x1, FOLFOXIRI x1, FOLFIRI x5
12/19 Liver resect #2
02/20 Ileo reversed
03/20 NED (PET+MRI)
06/20 NED (CT+MRI)
07/20 Clear scope

Claudine
Posts: 385
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Colon tumor metastasis to pelvis

Postby Claudine » Tue Sep 24, 2019 11:23 am

Hi there Gloriamazz,
I will concur with Rock_Robster - if the met is a bone met, then my understanding is that chemo won't have a very big effect on it. Radiation - such as SBRT - seems to be more effective.
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A
No primary (involuted?)
Lytic tumor L4 vertebrae, EBRT 04/18, SBRT 02/19
Resect small intestine 05/18 (no cancer - Crohn's)
Failed adjuvant Xelox
Folfiri + Avastin 03/19 to 01/20
6.7 cm left adrenal mass 03/19, successful resection 02/20
CEA since 03/19: high 58, low 3.2, now 4.4
Scan 03/19: Multiple small lung nodules up to 5mm
Scan 12/19: one 1mm stable nodule
PET 04/20 uptake by L4
L3-L4-L5 fusion surgery and residual tumor removal 05/20


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