I came cross a research paper, published recently in Science, by an MIT team. The team developed a vaccine that could increase the numbers of CAR-T Cells in human body by up 200 times. Therefore, it would become realistic that CAR-T cells are to kill solid tumors. They plan to start clinical trials in 1-2 years.
Link to the paper:https://science.sciencemag.org/content/ ... siteid=sci
It seems solid tumors are more different to treat than liquid tumors. I am closely following the progress of Prof. Ronald Levy'work of Stanford University. Their cancer vaccine that made a big splash in Jan 2018 is currently only being tested in slow glowing Lymphomas, in combination of radiation.https://www.cancer.gov/news-events/canc ... tu-vaccine
01.24.14 Male, DX @54 Rectosigmoid Cancer, MRI: T3N0M0
03.19.14 Completed 5-week Radia+Xeloda
05.07.14 Had surgery
02.25.15 CT showed liver and L4 Spine involvement.
03 - 08.15, folfox + Avastin
08 - 07.17, 5FU + leucovorin + Avastin for Maintenance
07 - 01.18, Folfuri + Avastin
02.07.18 - 03.06.19, Centuximab + Irinotecan
90 rounds of chemos received (as of 12.27.18)
MSS, KRAS wild type, BRAF wild type
TMB = 12 mut/MB
03.14.19 - Keytruda
05.16.19 - Folfox + Avastin