Congrats on your response - that your liver mets shrunk that much in 3 months time is really good news. Have a look at my sign below. FWIW, there are a few similarities that you may find encouraging: we both have/had a transverse colon resect immediately following Dx - ahead of attacking the liver mets that seem to respond so well to the meds. And your nice CEA readings seem to reflect what's happening in the liver. You may well be one of the lucky ones for whom CEA is a good indicator of cancer activity.
hopefulandstrong wrote:. . . Curious to know if any of you have seen tumors continue to shrink on meds.
My docs started out with CAPOX-Avastine right from the beginning, with shrinkage from week 10 which is quite comparable to your shrinkage of 30% at month 3.
I haven't heard of your EBC/triplet therapy, but it looks pretty effective, so far. Is it one of the new targeted treatments, may be?
I completed all the planned (8) rounds of CAPOX and may have been going into the liver surgery clean of cancer, as pathology couldn't find any living cancer cells in the piecesremoved. Have been NED with stable/low CEAs since (Oct 2013). I wish you to do similarly.
Dec 2012 - CC
2 unresect liver mets, CEA 41.8 (MM 65yrs)Jan 2013 - colectomy @ spleen
2/26 nodes IVa T3N1bM1a
Feb-Jul - 1x Xelox-7x Xelox/Avastin (neo adjuv), shrinkage from #3
Aug - 2 PV embolizations (both failed)Sep 2013 - R liver resect
, 25d hosp (liver failure/delirium, lung emboli, encephalopathy), cancer dead (pCR)
2014/15 - recovery, scopy: 2 polyps
2016 - new town, new lifeJune 2018 - 5 yr mark
, scopy: 2 polyps
1.3-1.4 CEA/clean CTs: 4x2014, 6x2015-17, 2x2018-19 , next June 2020