NHMike wrote:The genomic stuff is quite complicated. Here is a page which lists Colorectal Cencer tumor mutations and there are well in excess of 100 of them: http://targetedcancercare.massgeneral.org/My-Trial-Guide/Genes/KRAS/G12D-(c-35G-A).aspx
The page describes what the mutation is and what it does but the language assumes some level of university biology so it can be difficult to understand but it provides an explanation of what's happening to you on a molecular level.
Some mutations are aggressive - and it would be good for your oncologist to know if you have one of those. Some mutations have targeted therapies. In general, with CRC, you just get 5FU and Oxaliplatin but there are some targeted therapies for some mutations (and sometimes other conditions). Genetic testing (blood test; not a tumor sample) can determine if you have conditions that indicate that some drugs shouldn't be used or they may indicate that targeted therapies can be used.
So it's very complicated stuff and oncologists aren't always up to date on the latest clinical trials.
Thank you for posting this. Very informative.
I have one suggestion, though:
When you post a long URL like the one above, could you make sure that you include the URL inside the [ URL] ...[ /URL] tags? This is because there are some browsers out there that cannot parse a long URL like that one without having the tags in place. The troublesome URLs are the long, untagged ones that have a three dot ellipsis in them when they are displayed.