Husband has passed away from signet ring cell.

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Beloved fiancée
Posts: 8
Joined: Mon Jan 22, 2018 1:47 pm
Facebook Username: Silianai

Husband has passed away from signet ring cell.

Postby Beloved fiancée » Wed Jul 17, 2019 10:29 pm

Hello all, my husband has passed away from signet ring cell colon cancer on July 1st, 2019.

He was diagnosed on October 26, 2017. Stage 3, T4 signet ring mucinus Adenocarcinoma. 6 out of 12 lymph positive. Treatment standard folfox protocol.

January, 2019 recurrence. Multiple lymph nodes metastatic to the lungs. panitumumab with irinotecan for 3 months. Got suprapubic catheter. Had progression of disease.

May 2019, clinical trial at Hopkins.
Had bilateral nephrostomy placed.
Got married.
Hospitalized the day after wedding.
Had pneumonitis and several visit to the hospital.
June 14, 2019 came home hospice.

July 1st, 2019 became my angel!
Diagnosed 0ct 2017 colon Cancer
Procedure: right hemicolectomy
Stage: 3BT4 Mucinous with Signet-Ring Cell poorly differentiated. :(
Treatment: Started Jan. 2018 Folfox
Ct scan July 2018: clear with prominent mesenteric 11X9 mm
Pet scab Aug 2018: CLEAR
Now and Forever Cured! Thank to the LORD

stu
Posts: 1223
Joined: Sat Aug 17, 2013 5:46 pm

Re: Husband has passed away from signet ring cell.

Postby stu » Thu Jul 18, 2019 2:58 am

So sorry to hear that . Sending all my love at a difficult time .
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

MetastaticEquilibria
Posts: 61
Joined: Wed Jul 10, 2019 4:42 am
Location: Japan

Re: Husband has passed away from signet ring cell.

Postby MetastaticEquilibria » Thu Jul 18, 2019 6:45 am

My deepest condolences.
M55 Stage 4 Japan
12/16 Tumor rectal/sigmoid jct
1/17 Resect stage 2 T3N0M0+LVI
2-6/17 UFT+UZEL
7/17 Recurr.+2 liver mets stage 4
7-10/17 FOLFOX+Vectibix
11-12/17 FOLFOX+pelvic rad 60 Gy
1-7/18 FOLFOX+Vectibix
8-9/18 Liver protons 73 GyE
10-12/18 Xeloda+Avastin
2/19 New liver met
3/19 Liver protons 66 GyE
4/19 3 Lung mets
4-6/19 Vectibix
7-9/19 FOLFIRI+Cyramza
9/19 Biliary stent
10/19-now Lonsurf+Avastin
CEA 1.4-223 last 2: 130 74
CA19-9 2.8-232 last 2: 232 96
RAS wild MSS MET+ TP53-
UGT1A1*28 homo

Punky44
Posts: 403
Joined: Mon Oct 01, 2018 4:29 pm

Re: Husband has passed away from signet ring cell.

Postby Punky44 » Thu Jul 18, 2019 10:12 am

I am so sorry.
Caregiver to my amazing mom (68)
10/1/18 DX with rectal cancer; CEA 17 at diagnosis
T3N2M0
Total neoadjuvant therapy:
8 rounds Folfox 11/5/18 - 2/11/19
Short course radiation 3/14/19 - 3/20/19
Robotically assisted laparoscopic LAR 3/21/19
Pathology report says yT2N0M0 with 0/38 nodes
CEA 4/23: 2.1; 7/24: 1.9; 10/22: 2.6
6/28/19 Reversal and port out
10/22 — nodules on lungs—possible infection or mets—PET scheduled for 11/25

Me: 34, first colonoscopy 11/16/18—normal! Come back in 5 years.

boxhill
Posts: 404
Joined: Fri Apr 06, 2018 11:40 am

Re: Husband has passed away from signet ring cell.

Postby boxhill » Thu Jul 18, 2019 11:03 am

I am so sorry.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 nodes,5 mesentery nodes
5mm liver met out
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/4/18 FOLFOX
Neulasta 6/28
7/9/18 CT NED
11/20/18 CT NED. Enlarged spleen.
12/20/18 Liver MRI 5mm liver met? and 2 lymph nodes in porta hepatis
12/31/18 Keytruda
6/5/19 Triphasic CT LN and spleen normal, Liver node stable
6/28/19 Pause Keytruda, predisone for joint pain
7/31/19 Restart Keytruda
9/10/19 CT stable

fumaros
Posts: 273
Joined: Sat Jul 02, 2016 10:26 pm
Location: Syracuse, NY
Contact:

Re: Husband has passed away from signet ring cell.

Postby fumaros » Thu Jul 18, 2019 11:25 am

It hurts my hear for what you have been through. My prayers are with you.
Diagnosed 4/8/16, age 29
Colectomy 4/20/16
Stage III, T4bN1 Tumor 7x6.5x2. Muscinous Adenocarcinoma with SRC features
2/16 lymph nodes
Stage IV, Peri mets 5/2019
CEA 4/14/16 - 16.8
CEA 6/2/16 - 1.9
CEA 6/17/16 - 0.87, 7/16 - 1.33, 12/16 - 1.14, 4/17 - 0.6, 7/17 - 0.5, 10/17 - 0.9, 3/19 -5.8, 4/19 -10
FOLFOX began 6/24/16 - 11/25/16, FOLFIRI - 5/10/19
10 round FOLFOX, 2 round 5-FU & Leucovorin, 1 round FOLFIRI
MRI & CT 8/16 - NED, CT 12/16 - 10/17 - NED

AmyG
Posts: 301
Joined: Tue Dec 25, 2018 8:08 pm

Re: Husband has passed away from signet ring cell.

Postby AmyG » Thu Jul 18, 2019 8:29 pm

Words are inadequate, but I'm deeply sorry for your loss. I hope you have a support system to help you though this bullshit of losing your beloved husband.
42 dx @ 9wks pregnant w/baby #8 8/18
Sigmoid colon resection 9/18
Adenocarcinoma, G2, T3N0M0..or so we thought
KRAS/BRAF wild
Liver biopsy is malignant, stage iv now boys!
Delivered healthy baby 3/19
FOLFOX + Avastin 5/19
CEA 167 to 24 after 4 rounds
Liver resection 8/28/19
NED!! CEA 2.3
CEA 5.8 idk wtf is up with that, but everything else is clear!

macpudd
Posts: 120
Joined: Tue Jul 21, 2015 7:00 pm

Re: Husband has passed away from signet ring cell.

Postby macpudd » Thu Jul 18, 2019 9:42 pm

Condoleences to you and family and friends. I am so sorry for you and your husband going through such a hard time since his diagnosis.
Macpudd
Dx 10/13/2014 right hemicolectomy 10/15/2014 pT4b N0 M0
Folfox x12 from Dec 2014 to July 2015
01/16/18 tonic seizure hospital admission
01/17/18 ct and mri 2cm tumor on left side of brain
commenced anti epileptic and steroids and
insulin.
01/25/18 brain craniotomy 80% of tumour removed pathology says gbm4
6 weeks of rad and Temodar chemo and then 6 monthly cycles of Temodar
MRI in Oct no tumor
Mri Jan 2019 tumour growth Feb Pet scan tumour 6cm, no surgery, starting Avastin also Lomustine

natelaugh
Posts: 94
Joined: Wed Apr 03, 2019 11:40 pm

Re: Husband has passed away from signet ring cell.

Postby natelaugh » Thu Jul 18, 2019 10:04 pm

I wish all the best for you and hope you will feel better in time.

Nate.
Caregiver to 80M
DX:CC,RC,desc
11/2018 rightPain
1/19/19 scopy,path
1/23 CTscan
2/19 surgery
2/26-2/28 NGTube
2/28-3/14 TPN bc ileus
3/2 2nd surgeryCloseOpenWound
3/4-3/28 woundVac
size: 6cm Adenocarcinoma
grade Poorly
Stage IIIC T3N2aMx
PositiveLymph:5of28
BaselineCEA:68
LVI:Y
PNI:N
Surgical margins:clear
MSI:MMR (MLH1, MSH2, MSH6, PMS2) Intact nuclear expression
Lynch status:N
Laparascopic, partial colectomy
CEA:3/28/19 2.8
Chemo:4/16/19-9/17/19 5FU,12cycles,every 14days,leucoverin,zofran,Dexamethasone

CrossfitChick1980
Posts: 53
Joined: Wed Nov 25, 2015 9:40 pm

Re: Husband has passed away from signet ring cell.

Postby CrossfitChick1980 » Thu Jul 18, 2019 11:09 pm

So sorry! Hugs to you and your family.
Caregiver to DH dx with Adenocarcinoma of Small Intestine
Mar14- Small Bowel Resection (dx @31)
May14-Oct14: Folfox
Apr15- Liver mets
Jun15- Xeloda/Oxalyplatin
Oct15- Folfiri/Avastin
Dec15- Liver Mets, lymph nodes shrinking.
Apr16- Liver mets gone! lymph nodes stable
Jun16- Avastin/Xeloda (MSS, KRAS)
Jul16- Maintenance Chemo
Jun18- Cancer is back in liver
Sep18- Lonsurf
Oct18- Therasphere txment (failed)
Dec18- Folfiri/Avastin
Dec 22 2018- He is no longer suffering- My Love is sleeping in Peace

jmn
Posts: 48
Joined: Sat Aug 11, 2018 8:20 pm
Location: New York/Philadelphia

Re: Husband has passed away from signet ring cell.

Postby jmn » Fri Jul 19, 2019 12:24 am

So sorry for your loss. My deepest sympathies to you and your family.
DX: CC, 7-9-18 @ age 61, male
Severe anemia (4.5 g/dl), 5-11-18; colonoscopy, 6-29-18
Lap-assisted right hemicolectomy, 7-16-18
G2, moderately differentiated adenocarcinoma in cecum, 4.2 x 3.7 x 0.7 cm
Stage IIB, pT4aN0 (first pathology DX: pT3N0)
0/24 lymph nodes, LVI present, PNI present, surgical margins clear, MSS
CEA: 3.0 (pre-op, 7-10-18); 0.7 (post-op, 8-8-18)
TX: Xeloda (capecitabine) monotherapy, 10-16-18 to 4-21-19
CEA: 4-19, 3.4; 5-19, 3.0; 7-19, 3.0
NED: 5-28-19 :D
Clear colonoscopy, 7-15-19 :D

NHMike
Posts: 2335
Joined: Fri Jul 21, 2017 3:43 am

Re: Husband has passed away from signet ring cell.

Postby NHMike » Fri Jul 19, 2019 4:41 am

I’m sorry for your loss and struggle. I do remember when you started posting here.
6/17: ER rectal bleeding; Colonoscopy
7/17: 3B rectal. T3N1bM0. 5.2 4.5 4.3 cm. Lymphs: 6 x 4 mm, 8 x 6, 5 x 5
7/17-9/17: Xeloda radiation
7/5: CEA 2.7; 8/16: 1.9; 11/30: 0.6; 12/20 1.4; 1/10 1.8; 1/31 2.2; 2/28 2.6; 4/10 2.8; 5/1 2.8; 5/29 3.2; 7/13 4.5; 8/9 2.8, 2/12 1.2
MSS, KRAS G12D
10/17: 2.7 2.2 1.6 cm (-90%). Lymphs: 3 x 3 mm (-62.5%), 4 x 3 (-75%), 5 x 3 (-40%). 5.1 CM from AV
10/17: LAR, Temp Ileostomy, Path Complete Response
CapeOx (8) 12/17-6/18
7/18: Reversal, Port Removal
2/19: Clean CT

Gravelyguy
Posts: 261
Joined: Thu Jul 05, 2018 6:03 pm

Re: Husband has passed away from signet ring cell.

Postby Gravelyguy » Fri Jul 19, 2019 7:56 am

I am so sorry for your loss. I am at a loss for words but know that there are people praying for you as you go through this awful time.

Dave
6/17 dx mRC t3n1m1 very low rectal tumor 2 liver Mets 1.3 cm and .9 cm

6/17 begin 4 rounds Folfox w/Vectibix
9/17 short course radiation
10/17 rectal and liver resection LAR with coloanal anastomosis (no rectum left)
11/17-3/18 8 rounds Folfox
6/18 still NED!! Takedown
8/28/18 still NED! CEA .8 new low for me
10/18/18 colonoscopy clear
12/12/18 clear scans, CEA .9 still NED!
6/11/19 clear scans CEA 1.0

DarknessEmbraced
Posts: 3381
Joined: Sat Nov 01, 2014 4:54 pm
Facebook Username: Riann Fletcher
Location: New Brunswick, Canada

Re: Husband has passed away from signet ring cell.

Postby DarknessEmbraced » Sat Jul 20, 2019 10:47 am

I'm so very sorry for the loss of your husband!*hugs*
Diagnosed 10/28/14, age 36
Colon Resection 11/20/14, LAR (no illeo)
Stage 2a colon cancer, T3NOMO
Lymph-vascular invasion undetermined
0/22 lymph nodes
No chemo, no radiation
Clear Colonoscopy 04/29/15
NED 10/20/15
Ischemic Colitis 01/21/16
NED 11/10/16
CT Scan moved up due to high CEA 08/21/17
NED 09/25/17
NED 12/21/18
Clear colonoscopy 09/23/19
Clear 5 year scans 11/21/19- Considered cured! :)

User avatar
SilverWedding
Posts: 71
Joined: Sat May 18, 2019 5:54 am
Facebook Username: Cynthia Harding Marshall

Re: Husband has passed away from signet ring cell.

Postby SilverWedding » Sat Jul 20, 2019 9:52 pm

I’m so sorry. May God strengthen and provide right now.

Cynthia
DH, 56, Sigmoid & rectum
Adenocarcinoma 2cm
 G2: Moderately differentiated
T3N2aM0
Stage IIIb
LN 6/22
5/19 Baseline CEA value - 18.9
Lymphovascular invasion (LVI): present
Perineural invasion (PNI): not identified
Surgical margins: proximal -negative; distal - negative 1.5cm; circumferential - negative 1mm)
MSI status: Waiting‬
Lynch status: ?
KRAS/BRAF: ?
Open Restorative Proctectomy, J-Pouch Coloanal Anastomosis, Loop Ileo w/Appendectomy
Neo-adjuvant Xeloda/radiation
Adjuvant Chemo: to begin 11/19


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