Yeah, I remember sometime around round 8 when people would ask how I was feeling, I'd say "You know, I have to admit that this is starting to wear on me."
it's cumulative. At a certain point, you start to bounce back less--and less rapidly--than in earlier rounds, even if you have been lucky up til then. But eventually it does get better. Then you can start to feel the effects of the next kind of treatment, such as immunotherapy, LOL!
As I think I said elsewhere, I used to bound into the infusion center like the youngest and healthiest person there. Now, on Keytruda, my much longed-for miracle drug, I'm hobbling in like a crippled old lady.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 nodes,5 mesentery nodes
5mm liver met out
pT3 pN2b pM1
BRAF wild, KRAS G12D
7/18 and 11/18 CT NED
12/18 MRI 5mm liver mass, 2 lymph nodes in porta hepatis
6/19 Multiphasic CT LNs normal, Liver stable
6/28/19 Pause Key, predisone for joint pain
7/31/19 Restart Key
9/19 CT stable
Pain: all fails but Celebrex
12/23/19 CT stable
5/19 MRI stable/NED
8/20 MRI NED