Radial margin involved

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kristen007
Posts: 4
Joined: Fri Jul 12, 2019 5:43 am

Radial margin involved

Postby kristen007 » Fri Jul 12, 2019 6:36 am

Hi,

I am new and pT3 and N1a.
I had sigmoid resection a week ago.(Laparoscopy)
I just got a patholoy report and I found "Radial margin is involved(RPM).

I researched and it is rare in colon cancer and makes survival rate much lower.
Also I found in colon cancer there is not enough research than in rectal cancer.
I am so worried about RMP.
I am a wife and a mom to 5 month old twins.
Please reply if you have any idea for RMP in colon cancer.
Last edited by kristen007 on Tue Jul 16, 2019 10:20 pm, edited 1 time in total.

kristen007
Posts: 4
Joined: Fri Jul 12, 2019 5:43 am

Re: Radial margin involved

Postby kristen007 » Fri Jul 12, 2019 12:06 pm

I am a bit confused now.
In the begining of the report, it said "Proximal, distal, and mesenteric resection margins, negative for malignancy. "

But also later it said below.
"MARGINS: 
For resection specimens only: 
Proximal Margin:   Uninvolved by invasive carcinoma 
Distal Margin:   Uninvolved by invasive carcinoma 
Radial or Mesenteric Margin:    Involved by invasive carcinoma"

stu
Posts: 1163
Joined: Sat Aug 17, 2013 5:46 pm

Re: Radial margin involved

Postby stu » Sun Jul 14, 2019 4:00 am

Hi ,

Welcome to the forum .

I take it you had a right side ascending resection ?
I really think you would benefit from your surgeon going through this with you . I had a quick look and even the researchers flagged up limitations to the studies as the selected group seemed to all be starting at different base lines . Some with very invasive tumours and others not so much but both been measure under the same banner . Only had a quick look and I am no researcher !!!

One thing I have learnt about analysing information relating to cancer is despite it being a harder one there are many variables that lead to recurrence.

My mum’s disease had spread at the point of diagnosis but I can testify that her health has been positively impacted purely on her bodies response to chemo . Knocked the spread right of the scans !!! A good scanning protocol , getting in quickly and treating anything that popped up .
There are so many , many variables . They will take it into consideration along with cell type , lymph node involvement and decide if you need chemo etc .

Chemo can be a very powerful treatment tool and again a variable as individual patients respond in so many different ways .

In terms of handling information that is not as favourable as it might be . My mum did the following . Accept it was a reality that needed to be factored in when tailoring the individual treatment plan . However reject it firmly as a prognostic tool for your overall survival. My mum is ten years into a stage 4 diagnosis. You are an individual not a statistic.

Hope you get the opportunity to chat this through with your surgeon soon .
Take care ,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

User avatar
Green Tea
Posts: 202
Joined: Mon Oct 24, 2016 10:48 am
Location: Nusa Tenggara

Re: Radial margin involved

Postby Green Tea » Sun Jul 14, 2019 7:16 am

I would recommend downloading this document and discussing all of the sections on radial margins with your surgeon, and ask for complete explanation.

http://surgpathcriteria.stanford.edu/gi ... table.html

Also, you can access rp1954's comments about peri-operative Cimetidine and peri-operative Celecoxib here: This is for protection against possible spread during/after surgery:

https://coloncancersupport.colonclub.com/viewtopic.php?f=1&t=57693&p=454654#p454654

You can also read about Stage III member lpas' successful experience using both of these drugs for protection. See her signature:
memberlist.php?mode=viewprofile&u=93007

Question: Was it a Complete Mesocolic Excision (CME) that you had? A sigmoid colectomy? A left hemi-colectomy?
https://www.sages.org/meetings/annual-meeting/abstracts-archive/laparoscopic-complete-mesocolic-excision-cme-for-colon-cancer-study-design-and-preliminary-outcome-from-an-randomized-controlled-trial-nct01628250

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998025/

kristen007
Posts: 4
Joined: Fri Jul 12, 2019 5:43 am

Re: Radial margin involved

Postby kristen007 » Mon Jul 15, 2019 8:34 am

Thank you for your replies.
It was Sigmoid colon, partial colectomy.

Thank you for all your posts~


Kristen007

kristen007
Posts: 4
Joined: Fri Jul 12, 2019 5:43 am

Re: Radial margin involved

Postby kristen007 » Tue Aug 13, 2019 11:23 pm

They gave me the updated report.
They said there was a typographical error.
It is " Uninvolved ". :shock: :)

stu
Posts: 1163
Joined: Sat Aug 17, 2013 5:46 pm

Re: Radial margin involved

Postby stu » Wed Aug 14, 2019 1:34 am

Oh my ! Is that not just the best news . Take it and run .
Bit nerve wracking but it’s good news all the way for you . So pleased it was an admin error and your in a much better position going forward .
Take care,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .


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