Liver met near artery and bile duct

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Witherap
Posts: 3
Joined: Fri Jul 05, 2019 10:08 am

Liver met near artery and bile duct

Postby Witherap » Fri Jul 05, 2019 10:32 am

Just curious, outside of chemo, what the options are for small hepatic mets close to ducts/arteries?

boxhill
Posts: 355
Joined: Fri Apr 06, 2018 11:40 am

Re: Liver met near artery and bile duct

Postby boxhill » Fri Jul 05, 2019 1:43 pm

Y90, possibly?

Definitely immunotherapy, if you aren't lumping that in with chemo.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemi
11 of 25 nodes,5 mesentery nodes
5mm liver met out
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/4/18 FOLFOX
Neulasta 6/28
7/9/18 CT NED
11/20/18 CT NED. Enlarged spleen.
12/20/18 Liver MRI 5mm liver met? and 2 lymph nodes in porta hepatis
12/31/18 Keytruda
6/5/19 Triphasic CT LN and spleen normal, Liver node stable
6/28/19 Pause Keytruda, predisone for joint pain
7/31/19 Restart Keytruda
9/10/19 CT stable

Witherap
Posts: 3
Joined: Fri Jul 05, 2019 10:08 am

Re: Liver met near artery and bile duct

Postby Witherap » Sat Jul 06, 2019 12:32 pm

Unclear. Wondering about nanoknife and cryoablation too.

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Jack&KatiesMommy
Posts: 595
Joined: Wed Dec 21, 2011 1:08 pm
Location: Columbus, OH

Re: Liver met near artery and bile duct

Postby Jack&KatiesMommy » Sat Jul 06, 2019 10:06 pm

In February 2013 I had Irreversible electroporation (I think it is now called Nanaoknife) at Memorial Sloan Kettering Cancer Center on a tumor in my liver that was too close to my arterial artery to remove it or even to do RFA since the blood in the artery would cool the RFA too much for it to be effective on the cancer cells closest to the artery. It was very noninvasive...the tumor was eliminated and I have not had a recurrence.
Cynthia
Mommy to Jack (8) now (16) and Katie (4) now (12)
(My Most Precious Things)
Dx 8/11 Stage IV CRC (liver mets) CEA 2,600+
9/11 Folfiri 2/12: Failed Liver Resection
5/12 HAI pump/removed primary
4/13 Liver Resection
8/13-12/15 (10) RFAs lungs
5/17: Upper Left Lobe of lung resected.
02/18: 3 new mets lymph nodes lung:
05/18: Keytruda (MSS w/Intermediate TMB): CEA: 66.4, 39.2, 23.8, 13, 3.5 1.8, 1.0, 2.8 3.9, 5.0, 5.6, 1.5, .8, .8, 1.1, 1.1, .7
7/18; 9/18; 11/18; 2/19 Clear CT scans

Witherap
Posts: 3
Joined: Fri Jul 05, 2019 10:08 am

Re: Liver met near artery and bile duct

Postby Witherap » Sun Jul 07, 2019 8:36 pm

Thanks!

MetastaticEquilibria
Posts: 41
Joined: Wed Jul 10, 2019 4:42 am
Location: Japan

Re: Liver met near artery and bile duct

Postby MetastaticEquilibria » Thu Jul 11, 2019 5:01 am

Just to throw another possibility out there: proton beam therapy, which I have had done on some inoperable liver mets.
M55 Stage 4 (Japan)
12/16 Tumor rectal/sigmoid jct
1/17 Resect stage 2 T3N0M0+LVI
2-6/17 UFT+UZEL
7/17 Recurr.+2 liver mets stage 4
7-10/17 FOLFOX+Vectibix
11-12/17 FOLFOX+pelvic rad (x/gamma 60 Gy)
1-7/18 FOLFOX+Vectibix
8-9/18 Liver rad (protons 73 GyE)
10/18-12/18 Xeloda+Avastin
2/19 New liver met
3/19 Liver rad (protons 66 GyE)
4/19 3 lung mets
4-6/19 Vectibix
7/19-now FOLFIRI+Cyramza
8/19 Lung mets stable
CEA 1.4-223 now 12.6
CA19-9 2.8-105 now 65
RAS wild MSS MET+func TP53-func
UGT1A1*28 homo

mariane
Posts: 675
Joined: Sun Sep 13, 2015 6:16 pm

Re: Liver met near artery and bile duct

Postby mariane » Mon Jul 29, 2019 2:41 pm

HAI pump. My larger tumors were all badly located. 1 abuting vena cava. After shrinking they got all removed. Good luck!
mom of now 10 years old twins, dx @ 40 in 6/2015 with upper rectal cancer, 10+ liver mets, CEA 140
chemo: 8/2015 - 10/2016 - 4xFOLFIRINOX, 2xFOLFOX, 8xFOLFIRI, 10x5FU, HAI pump -12xFUDR
4 surgeries, complete pathological response
CEA<2 since 10/2015
NED since May 2016

I praise God for every day with my family!

mariane
Posts: 675
Joined: Sun Sep 13, 2015 6:16 pm

Re: Liver met near artery and bile duct

Postby mariane » Mon Jul 29, 2019 2:42 pm

However, HAI= chemo. I am sorry. I skimmed.
mom of now 10 years old twins, dx @ 40 in 6/2015 with upper rectal cancer, 10+ liver mets, CEA 140
chemo: 8/2015 - 10/2016 - 4xFOLFIRINOX, 2xFOLFOX, 8xFOLFIRI, 10x5FU, HAI pump -12xFUDR
4 surgeries, complete pathological response
CEA<2 since 10/2015
NED since May 2016

I praise God for every day with my family!


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