My wife took it after recurrence after 4 years of NED. It is doing the job and shrinking new growth. It is not an easy drug to take, I know. She is happy to keep taking it as long as it is showing progress working again. On treatment day she naps, but the following days are progressively better and by day 3 she is back to normal.
D/H 47 years old, 10/2014, Stage IV M/CRC, nodes 12/15, para-aortic, 5 cm sigmoid resection, positive Virchow. KRAS mut, MSS, Highly Differentiated, Lynch Neg, 5FU/LV and Avastin 1 YR (Oxi for 5 months) NED 05/2015, Zeloda/Bev since 01/2016. 02/2019 recurrence para-nodes, back to 5FU/LV Oxy/Bev, pending genetic results. "...Perseverance is not a long race; it is many short races one after the other."-Walter Elliot