Anyone done oxiplatin twice?

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Trying
Posts: 170
Joined: Sun May 13, 2018 10:11 pm

Anyone done oxiplatin twice?

Postby Trying » Tue Jun 11, 2019 10:14 am

I made a decision with my dr to do 4 roynds of oxiplatin since it worked ao well last year. Im scared because i hear the effects are worse second time. Anyone do a second round and how was it?
38 yr old single mom of almost 2 yr old.
Colon cancer stage IV 10 liver mets and peri metApril 2018
Folfox as of June 2018
Down to 2 mets in liver dec 2018.

kandj
Posts: 258
Joined: Sun Sep 27, 2015 11:29 am

Re: Anyone done oxiplatin twice?

Postby kandj » Tue Jun 11, 2019 12:49 pm

DH did about 13 rounds total of it. They cut him from it when he started having trouble swallowing *neuropathy in his throat*. He had about 7 rounds before liver surgery and then another 6 a year later after a reoccurrence
wife to DH, dx 8/15 stage IV @36, numerous unresectable liver Mets
resection and HAI placed 12/15
Liver resection 5/19/2016 15-20 mets removed (surgeon lost count, but it hopeful he got it all!)
Recurrence 7/2017 4 Liver mets and one possible lung met
Radiation on liver Mets 12/17
Lung met 10/18
VATS on lung met 11/18 started xeloda
chemo break, nothing seen on scans 6/19 or 8/19 Hopeful

stu
Posts: 1183
Joined: Sat Aug 17, 2013 5:46 pm

Re: Anyone done oxiplatin twice?

Postby stu » Tue Jun 11, 2019 1:06 pm

Hi ,
My mum has had it twice . 10% less the second year and made a big difference with the side effects . The second year was much better .
Take care,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

WarriorSpouse
Posts: 197
Joined: Tue Aug 16, 2016 9:02 pm

Re: Anyone done oxiplatin twice?

Postby WarriorSpouse » Wed Jun 12, 2019 12:30 am

My wife took it after recurrence after 4 years of NED. It is doing the job and shrinking new growth. It is not an easy drug to take, I know. She is happy to keep taking it as long as it is showing progress working again. On treatment day she naps, but the following days are progressively better and by day 3 she is back to normal.

Good luck!
WS
D/H 47 years old, 10/2014, Stage IV M/CRC, nodes 12/15, para-aortic, 5 cm sigmoid resection, positive Virchow. KRAS mut, MSS, Highly Differentiated, Lynch Neg, 5FU/LV and Avastin 1 YR (Oxi for 5 months), Zeloda/Bev since 01/2016. 02/2019 recurrence para-nodes, back to 5FU/LV Oxy/Bev. It is working again. "...Perseverance is not a long race; it is many short races one after the other."-Walter Elliot

Dagmar
Posts: 11
Joined: Wed Aug 07, 2019 2:02 pm

Re: Anyone done oxiplatin twice?

Postby Dagmar » Tue Aug 20, 2019 2:50 pm

Hi, I am starting oxiplatin again. I had 12 sessions in 2013. My cancer marker went up to 55. I am scared of all the side effects. Ordered heated insoles for the Cold Winter months. Did anyone else have good results the second time? Did the cancer marker go down?

tbt4snow
Posts: 26
Joined: Sat Oct 27, 2018 3:16 pm
Facebook Username: Tina tran

Re: Anyone done oxiplatin twice?

Postby tbt4snow » Wed Aug 21, 2019 5:26 am

I did 12 round last year. Recurring after 6 months, surgery then oxi at 60%. Ct scan is clear but my cea go up from 1.9 to 3.5 after 5 treatments. Neuropathy is not as bad this time compared to the last. I do Accupunture one or twice a week and have ice chip in my mouth. Ice pack on my feet during oxi infusion. This helps with cold sensitivity. I learn this from Healio.com under article “ Ice chips a ‘no-cost intervention’ to improve oxaliplatin-induced oral symptoms” if you want to check that out.
Good luck.
DX: CC stage 4/w ovaries & omentum mets in 12/17 49/F
High grade pT3N1bM1b sigmoid Adenocarcinoma colon
MSS-h TMB=16, NRAS-mutant
Lymph nodes: 1/2 left colic; 3/8 regional
12/2017: Exploratory laparotomy & resect of sigmoid & ovaries
Folfox/avastin 12 sessions from 1/8-6/18. 6/18 CEA 2.1
1/19: CT shows peri mets;
CEA: 12/18 5.1, 1/7/19 7.9; 1/15/19 9.1; 1/30/19: 10.6
4/3/2019 CRS/HIPEC after 4 Folfiry sessions...

stu
Posts: 1183
Joined: Sat Aug 17, 2013 5:46 pm

Re: Anyone done oxiplatin twice?

Postby stu » Wed Aug 21, 2019 5:57 am

My mum got the same shrinkage the second time round as she achieved the first . It was during one of the worst winters we have had . We had her well wrapped up . You could only see her eyes . Kept the house nice and warm and all was well .
She had a reduced dose the second time by 20% and it still worked but reduced some of the worst side effects . She was out for her coffees and enjoyed family life when she could .
Take care,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

Dagmar
Posts: 11
Joined: Wed Aug 07, 2019 2:02 pm

Re: Anyone done oxiplatin twice?

Postby Dagmar » Fri Aug 23, 2019 6:18 am

Thank you both for posting these last massage. Very much nedeed as I am in pain and nearly want to give up. I love you for that!

There is a medicin for neuropathy called Gabapentin.


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