Numerous tiny lung lesions??

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claudine
Posts: 809
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Numerous tiny lung lesions??

Postby claudine » Fri May 24, 2019 12:42 pm

My husband had his mid-chemo scan on Tuesday, after 5 cycles of Folfiri + Avastin (out of 12 scheduled - he had the 6th yesterday). His CEA level had been dropping regularly since he started mid March and we were pleased to learn that his adrenal gland tumor shrunk by 35% (from 5.3cm to 3.5cm). His lumbar spine tumor is "looking good" (in the words of his onc).
What we were not expecting, though, is that the scan detected numerous small lesions in both his lungs. Fortunately, those did not appear after he started treatment - the techs went back to his January 17th PET scan and they were already there, just too small to "light up" (they're all smaller than 3mm). Apparently they're also shrinking, although it's hard to quantify by how much because they were tiny to begin with.

So... More chemo, at this point they're too numerous (and small) for resection to make any sense. I was glad to read on this forum about laser options, in case the chemo cannot control them. It looks like MD Anderson does this in the US, probably other centers, I haven't looked yet but I like knowing that there are options "just in case"...

Anyone out here has had such small lesions completely disappear with chemo?
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A, no primary

Tumors: L4 04/18; left adrenal gland & small lung nodules 03/19
rectum 02/22 (pT3 pN0 stage 2A); L3 09/22

Surgeries: intestinal resect. 05/18 (no cancer - Crohn's); adrenalectomy 02/20
L3-L4-L5 fusion and corpectomy 05/20; LAR 04/22; ileo reversal 09/22
L2-L3 fusion and corpectomy 09/22

Treatments: EBRT 04/18; SBRT 02/19; Failed adjuvant Xelox ; Folfiri/Avastin 03/19 - 01/20
adjuvant chemorad (Xeloda) 06/22; SBRT 11/22; Xeloda/Avastin since 01/24

Butt
Posts: 41
Joined: Mon Mar 11, 2019 10:48 pm

Re: Numerous tiny lung lesions??

Postby Butt » Sun May 26, 2019 7:50 pm

You need to have less than 10 mets in lungs to do sERT.,it is radiation.

stu
Posts: 1614
Joined: Sat Aug 17, 2013 5:46 pm

Re: Numerous tiny lung lesions??

Postby stu » Mon May 27, 2019 4:18 pm

Hi ,
Sorry to hear about the lung issues although it does sound as though they are particularly small and responsive.
Dr Drewes in Germany is doing laser surgery on the lungs .
Take care,
Stu
supporter to my mum who lives a great life despite a difficult diagnosis
stage4 2009 significant spread to liver
2010 colon /liver resection
chemo following recurrence
73% of liver removed
enjoying life treatment free
2016 lung resection
Oct 2017 nice clear scan . Two lung nodules disappeared
Oct 2018. Another clear scan .

claudine
Posts: 809
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Numerous tiny lung lesions??

Postby claudine » Tue May 28, 2019 9:31 am

Thanks; yes, at this stage chemo seems to be the way to go. Hopefully it'll take care of all the lesions; or most of them, and if some are resistant and keep growing, we'll look into radiation. Next scan will take place sometimes this summer after another 6 Folfiri cycles...
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A, no primary

Tumors: L4 04/18; left adrenal gland & small lung nodules 03/19
rectum 02/22 (pT3 pN0 stage 2A); L3 09/22

Surgeries: intestinal resect. 05/18 (no cancer - Crohn's); adrenalectomy 02/20
L3-L4-L5 fusion and corpectomy 05/20; LAR 04/22; ileo reversal 09/22
L2-L3 fusion and corpectomy 09/22

Treatments: EBRT 04/18; SBRT 02/19; Failed adjuvant Xelox ; Folfiri/Avastin 03/19 - 01/20
adjuvant chemorad (Xeloda) 06/22; SBRT 11/22; Xeloda/Avastin since 01/24

claudine
Posts: 809
Joined: Tue Mar 12, 2019 2:41 pm
Location: Montana

Re: Numerous tiny lung lesions??

Postby claudine » Wed May 29, 2019 10:31 am

Got the actual scan report. Nodules either shrinking since last scan (March 14) - 5mm to 3mm, 3.5mm to 1mm, and 4mm to 2mm, or remaining stable (less than 2mm in size). Fingers crossed Folriri + Avastin keep doing its job!
Wife of Dx 04/18 (51 yo). MSS, KRAS G12A, no primary

Tumors: L4 04/18; left adrenal gland & small lung nodules 03/19
rectum 02/22 (pT3 pN0 stage 2A); L3 09/22

Surgeries: intestinal resect. 05/18 (no cancer - Crohn's); adrenalectomy 02/20
L3-L4-L5 fusion and corpectomy 05/20; LAR 04/22; ileo reversal 09/22
L2-L3 fusion and corpectomy 09/22

Treatments: EBRT 04/18; SBRT 02/19; Failed adjuvant Xelox ; Folfiri/Avastin 03/19 - 01/20
adjuvant chemorad (Xeloda) 06/22; SBRT 11/22; Xeloda/Avastin since 01/24


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