Molecular Advances in Colorectal Cancer Are "Only the Tip of the Iceberg"

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zephyr
Posts: 369
Joined: Thu Aug 18, 2016 7:31 am

Molecular Advances in Colorectal Cancer Are "Only the Tip of the Iceberg"

Postby zephyr » Fri May 17, 2019 6:35 pm

I thought this article was an interesting overview of CRC treatments.

https://www.onclive.com/publications/On ... xrZJUpGIKQ
Nov-2009 Early stage CRC, routine colonoscopy
2010-2014 F/U colonoscopies, all clear
Jun-2016 CRC during F/U colonoscopy, surgery, Stage 4, KRAS, MSS
Aug-2016-May-2018 Folfox, 5FU, Folfiri & Avastin
Aug/Sep-2018 YAG laser surgeries (Germany), 11 nodules removed
Nov-2018 clean CT scan
Mar-2019 New lung nodules
Apr-2019 Dec-2020 Xeloda/Avastin, SBRT, cont. Xeloda/Avastin
Mar-2021 Forfiri/Avastin
Mar-2022 Ablation & Thoracotomy
Feb-2023 Folfiri & Avastin
Nov-2023 Xeloda & Avastin

Pyro70
Posts: 156
Joined: Mon Jan 21, 2019 4:25 pm

Re: Molecular Advances in Colorectal Cancer Are "Only the Tip of the Iceberg"

Postby Pyro70 » Fri May 17, 2019 8:37 pm

Yeah, I had seen that. Good summary. Everyone should be ensuring they have been tested for the various actionable markers: trk/alk fusions, her2, msi/tmb, etc. I’ve seen oncologist discuss that they don’t know what to do about longer surviving patients that weren’t tested for trk fusions, if it’s worth going back and testing for a 1% chance. For me it is, so I would definitely check that it’s been done...
Dx Jan 2017 stage IVB w/ PC age 35
FOLFOX
SEP 17 HIPEC 1, anastamosis leak
XELODA
MAR 18 HIPEC 2
JUN 18, ileo reversal and 2nd anastamosis leak


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