Indeed Pyro70, if the SBRT is well-tolerated then it would be tempting.
It reminds me a bit of the Total Body Irradiation given before bone marrow transplants for leukaemia, except that the intent is entirely the opposite - to suppress the immune system prior to transplant. Will be fascinating to see how (if) radiation could also actually sensitise the immune system to tumour cells.
Male 37; Melbourne, Australia.
10/2018 Dx 3.5 cm RC adenocarcinoma, 12cm from AV
Mod diff (G2), EMVI+, LVI+, PNI-
3 local LN; 4 liver mets, resectable
pT3pN1apM1a; Stage IVa. MSS, NRAS (G13R)
CEA: Oct-18= 12; Nov-18= 14, Mar-19= 2.4, Aug-19 <2.0
11/18 - FOLFOX x 6
3/19 - Liver resection (open)
4-5/19 - 25 x pelvic radiation w Xeloda; complete metabolic response (TRG 3)
07/19 - ULAR (robotic), temp ileo. 1/27 LN positive
08/19 - Missed liver spot; plan to resect after chemo
08/19 - FOLFOX or FOLFORI x 4