Indeed Pyro70, if the SBRT is well-tolerated then it would be tempting.
It reminds me a bit of the Total Body Irradiation given before bone marrow transplants for leukaemia, except that the intent is entirely the opposite - to suppress the immune system prior to transplant. Will be fascinating to see how (if) radiation could also actually sensitise the immune system to tumour cells.
Male 37 years; Melbourne, Australia
10/2018 Dx: 3.5 cm rectal adenocarcinoma, 10 cm from verge. Well/mod diff (G1-2), T3bN1bM1a.
3 enlarged local lymph nodes and 4 liver lesions.
MSS, MMR-proficient, mutated in NRAS (G13R).
CEA: Oct-18 = 12; Nov-18 = 14, Mar-19 = 2.4
11/18 - 6 cycles neoadjuvant FOLFOX
12/18 - DVT, started clexane
3/19 - Liver resection, R0
4-5/19 - Long-course pelvic chemoradiation (45 Gy w/ Xeloda)
07/19 - Planned restaging scans and ULAR w temp ileo