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Peanut related to cancer spread?

Posted: Tue May 14, 2019 10:41 am
by Bostonzj
I read a paper a few days ago, saying the peanut consumption might help maretesis of the cancer cells, here is the link https://news.liverpool.ac.uk/2014/12/19 ... er-spread/

I was kind of freak out , I eat peanut butter a few days a week! After read this paper, I stop eating right away! Any body has any thought? My onco never mention that the peanut is prohibited..

Re: Peanut related to cancer spread?

Posted: Tue May 14, 2019 10:46 am
by Pyro
I think it’s ridiculous, everything in moderation.

Re: Peanut related to cancer spread?

Posted: Wed May 15, 2019 9:47 am
by GrouseMan
This study is not new it dates from 2014. The Liverpool page cites the following paper.

Here is a link to the original paper: https://www.ncbi.nlm.nih.gov/pubmed/25326505

No follow up that I can see from 2014. While they may still be studying this relationship much more needs to be done in my opinion. This all seems very speculative at this point as far as I am concerned. They are studying tumor cells - Not a clinical trial or even a pre clinical trial in mice where they contrast people or mice given peanuts and those who don't have peanuts. Just because this happens in isolated tumor growth media don't mean it is a significant mechanism in whole animals or people yet.

The interesting thing they say is "TF disaccharide (galactoseβ1,3N-acetylgalactosamineα-) is overexpressed by ~90% of human cancers" This I would think makes this TF disaccharide a very interesting target for immunotherapy to attack cancer cells that over express this on their cell surface. Trouble is this may be expressed in a lot of other cells as well.

If you like peanuts - maybe switch over to other nuts like pecans, walnuts, almonds etc. These tree nuts are probably better for you anyway. I like to eat a lot of nuts, as they are a better snack than chips and other things. Peanuts are however cheaper, and from what I understand in Asia often associated with a type of liver cancer due to a fungus that they can get that produces compounds called aflatoxins. Climate and the fact that a lot of peanuts are consumed in SE Asia the incidence of liver cancer associated with exposure to Aflatoxin is considerably higher than in the US or Europe. The sort of liver cancer associated with Aflatoxins are not very common outside of SE Asia. My father had this sort of liver cancer a couple of years ago, its very rare here. When they discussed this with him he thought it might have been from his time in Korea 60+ years ago.

Here is a link about Peanuts and Aflatoxins: https://www.cancer.gov/about-cancer/cau ... aflatoxins

GrouseMan

Re: Peanut related to cancer spread?

Posted: Mon May 20, 2019 7:42 pm
by CRguy
Thanks for that feedback GrouseMan !

I agree always interesting to find out new info ... BUTT ... not always exact science as reported.

Folks also need to remember that peanuts are not tree nuts,
they are legumes and the aflatoxicosis is almost unknown in N America
due to mandatory preventive measures.

Cheers
CRguy