Question about Xeloda scheduling/timing differences

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WriterGirl1969
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Re: Question about Xeloda scheduling/timing differences

Postby WriterGirl1969 » Wed Apr 17, 2019 10:21 am

rp1954 wrote:For stage 3s, 5FU intensity rather than long durations repeatedly seems to be a key success factor in permanently rooting out residual cancer cells or clusters. Just like some of the 3-4 month vs 6 month success rates, your catch on the 8 day peak is interesting. My question is for kill optimization, why not 8 0n + 6 off (two week schedule) or 8 on + 7 off (twice a month)? Congratulations on your successes, thinking for yourself, and sharing.

For stage IV or other mCRC, chemo choice is often a decision point after a nominally, completely "curative surgery" - intensity vs maintenance. If still mCRC, maintenance or metronomic may be required. Then the problem becomes intensity, by other means, and duration.


Great added note, RP. Thank you. I was on a very high dose of Xeloda, so your note is on the mark. Appreciate the additional info.
--Tracy
DX 3/4/2016 Colon Cancer; age 46 Mom of then 4-yr-old
Stage IIIB: T3N1M0
3/31/16 Surgery
4 to 10/2016: Xeloda Monotherapy
CEA: 10/16 0.56, 1/17 0.54
CT CLEAR: 3/6/17; 4/17/18; 4/16/19
NED 3 years
“If I can help somebody as I walk along, then my living shall not be in vain.”


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