rp1954 wrote:For stage 3s, 5FU intensity rather than long durations repeatedly seems to be a key success factor in permanently rooting out residual cancer cells or clusters. Just like some of the 3-4 month vs 6 month success rates, your catch on the 8 day peak is interesting. My question is for kill optimization, why not 8 0n + 6 off (two week schedule) or 8 on + 7 off (twice a month)? Congratulations on your successes, thinking for yourself, and sharing.
For stage IV or other mCRC, chemo choice is often a decision point after a nominally, completely "curative surgery" - intensity vs maintenance. If still mCRC, maintenance or metronomic may be required. Then the problem becomes intensity, by other means, and duration.
Great added note, RP. Thank you. I was on a very high dose of Xeloda, so your note is on the mark. Appreciate the additional info.
--Tracy