Pain and tingling of my left leg

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boswind
Posts: 49
Joined: Fri Apr 11, 2014 12:04 pm

Pain and tingling of my left leg

Postby boswind » Mon Mar 11, 2019 2:20 pm

I have been on Irinotecan and Cetuximab for the last 13 months. For the recent two months I have felt moderate pain and tingling of my left leg while my right leg and arms are not effected. I'd like to know if any one has or had similar symptoms of pain and tingling. Now I have to take Ibuprofen and Tylenol every 4 hours.

I will start Keytruda treatment this Thur (Mar 14). The pain and tingling have not gone or become less severe, although my last chemo of Irinotecan and Cetuximab was done 2 1/2 weeks (18 days) ago.
01.24.2014 Male, DX @54 Rectosigmoid Cancer, MRI: T3N0M0
03.19.2014 Completed 5-week Radia+Xeloda
05.07.2014 Had surgery
02.25.2015 CT showed liver and L4 Spine involvement.
03.2015 - 08.2015, folfox + Avastin
08.2015 - 07.2017, 5FU + leucovorin + Avastin for Maintenance
07.2017 - 01.2018, Folfuri + Avastin
02.07.2018 - 03.06.2019, Centuximab + Irinotecan
90 rounds of chemos received (as of 12.27.2018)
Current CEA: 9.8 as of 12.27.2018
MSS, KRAS wild type, BRAF wild type
03.14.2019 - starting Keytruda

boxhill
Posts: 189
Joined: Fri Apr 06, 2018 11:40 am

Re: Pain and tingling of my left leg

Postby boxhill » Mon Mar 11, 2019 4:05 pm

What does your oncologist say about it? Does it seems to radiate down your leg from the hip, and if so in the front or the back? Did you have any kind of precipitating event? Does it feel at all electric, or is it a dull bone ache? Is it positional? Is there swelling? It could be many things, including neuropathy, a clot, a pinched nerve, you name it. If you haven't consulted the doctor about it yet, I think you should, and make sure it is taken seriously. No point in being a hero. :)

I had pain that I would call almost electric--radiating down the front--from a nerve problem, years before CRC. I had wrenched my piriformis muscle, which was putting pressure on an adjacent nerve. Assiduous targeted stretches and so forth did no good. Couldn't sleep without hydrocodone or the like. What finally fixed it was accupuncture, which I think is really great for nerve-related issues.
F, 64 at DX CRC Stage IV
3/17/18 blockage, r hemicolectomy
11 of 25 nodes,5 of 5 mesentery nodes
0.5 cm sub-capsular liver met removed
pT3 pN2b pM1
BRAF wild, KRAS G12D
dMMR, MSI-H
5/4/18 FOLFOX
Neulasta 6/28/18
7/9/18 CT no masses or enlarged nodes, 2mm indeterminate lung nodule
11/20/18 CT same, Lung nodule likely calcified granuloma. Enlarged spleen.
12/20/18 Liver MRI 5mm liver met and 2 lymph nodes in porta hepatis, CT review shows progression of nodes on FOLFOX
12/31/18 Keytruda


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