Dandelion Root Extract

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mpbser
Posts: 953
Joined: Wed Apr 19, 2017 11:52 am

Dandelion Root Extract

Postby mpbser » Sat Feb 16, 2019 8:50 am

Does anyone use it?

I just bought some for my husband after reading this:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341965/
Wife 4/17 Dx age 45
5/17 LAR
Adenocarcinoma
low grade
1st primary T3 N2b M1a
Stage IVA
8/17 Sub-total colectomy
2nd primary 5.5 cm T1 N0
9 of 96 nodes
CEA: < 2.9
MSS
Lynch no; KRAS wild
Immunohistochemsistry Normal
Fall 2017 FOLFOX shrank the 1 met in liver
1/18 Liver left hepatectomy seg 4
5/18 CT clear
12/18 MRI 1 liver met
3/7/19 Resection & HAI
4/1/19 Folfiri & FUDR
5/13/19 HAI pump catheter dislodge, nearly bled to death
6-7 '19 5FU 4 cycles
NED

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GrouseMan
Posts: 888
Joined: Mon Aug 12, 2013 12:30 pm
Location: SE Michigan USA

Re: Dandelion Root Extract

Postby GrouseMan » Sat Feb 16, 2019 10:09 am

I read through this paper you reference and to me the evidence though there is not compelling. Calculations suggest that the amount of extract for a typical Male patient would be about 2.8 grams per day. That's for the extract as prepared in that paper. Seems like a lot to me and could result in GI issues. This paper also suggests 3 particular molecules in the extract are responsible for its effect. But further research showed other tested extracts of dandelion also said to be effective where of completely different chemical class of compounds. So different extracts contain different materials. Also note - the particular preparation of the extract is important. Just using dried dandelion its likely you will never obtain the correct dosage as the extraction and concentration process from the paper used a large amount of dandelion root to produce the extracted components. They do not indicate the amount of starting root they used and how much extracted material they ended up with. This is important.

That said - you can use at your own risk, but personally unless you made your own extract following the procedure from the paper - I think you are wasting your money. There is no way to know what you purchased is anything at all like the extract used by these researchers or even contains significant amounts of the compounds they claim in the published paper.

Here are a couple of additional references I located this morning:
from MSK's web site: https://www.mskcc.org/cancer-care/integ ... /dandelion
News report from someone doing the research: http://windsorcancerresearch.com/2017/1 ... ncologist/
https://www.snopes.com/fact-check/dande ... ls-cancer/

Even if you want to continue to try this. I suggest you let your oncologist know, as there is the possibility of drug interactions and the extract has shown to interfere with metabolism of other drugs.

Regards,

GrouseMan
DW 53 dx Jun 2013
CT mets Liver Spleen lung. IVb CEA~110
Jul 2013 Sig Resct
8/13 FolFox,Avastin 12Tx mild sfx, Ongoing 5-FU Avastin every 3 wks.
CEA: good marker
7/7/14 CT Can't see the spleen Mets.
8/16/15 CEA Up, CT new abdominal mets. Iri, 5-FU, Avastin every 2 wks.
1/16 Iri, Erbitux and likely Avastin (Trial) CEA going >.
1/17 CEA up again dropped from Trial, Mets growth 4-6 mm in abdomen
5/2/17 Failed second trial, Hospitalized 15 days 5/11. Home Hospice 5/26, at peace 6/4/2017

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CRguy
Posts: 10476
Joined: Sun Feb 10, 2008 6:00 pm

Re: Dandelion Root Extract

Postby CRguy » Sun Feb 17, 2019 8:00 pm

GrouseMan,
Thank you once again for your great input and links.

You have unique experience to help us sort through a lot of the pseudo science and wishful thinking hype
which appears regularly in the popular press ... AND ... legitimate "wet chemistry level" / mouse experiments
which are not yet ready for real world, human .... prime time !

I personally welcome all of your comments and feedback.

Best wishes
CRguy
Caregiver x 4
Stage IV A rectal cancer/lung met
17 Year survivor
my life is an ongoing totally randomized UNcontrolled experiment with N=1 !
Review of my Journey so far

Lee
Posts: 6207
Joined: Sun Apr 16, 2006 4:09 pm

Re: Dandelion Root Extract

Postby Lee » Sun Feb 17, 2019 8:52 pm

CRguy wrote:GrouseMan,
Thank you once again for your great input and links.

I personally welcome all of your comments and feedback.

Best wishes
CRguy


Ditto to what CRguy said, Thank you GrouseMan for all that you contribute here.

Lee
rectal cancer - April 2004
46 yrs old at diagnoses
stage III C - 6/13 lymph positive
radiation - 6 weeks
surgery - August 2004/hernia repair 2014
permanent colostomy
chemo - FOLFOX
NED - 16 years and counting!

AppleTree
Posts: 267
Joined: Fri Mar 18, 2016 8:16 am

Re: Dandelion Root Extract

Postby AppleTree » Mon Feb 18, 2019 12:44 am

Just an interesting note about dandelion root... one of my sisters had crippling rheumatoid arthritis. She digs up her own dandelion roots and makes a tea. This tea really makes her inflammation go down. Often times it prevents a visit to her specialist. I am not recommending it to anyone, I am just saying that my sister has had very good results with her home brew (anything "dandelion " that she buys is usually not effective).
Diag Feb 5, 2016 Age 45
3 cm tumor 5 cm from verge
Radiation + Xeloda pills - 3000mg 5x week
3/14 - 4/16 - 25 sessions
Shrank just over 50% L nodes 0/13
Remove rectum with temp Ileo 6/17
Reversal 7/20 due to infection
Acute hepatitis August. Chemo cancelled
June to September 2016 - 58 days in hospital

2017
6/16, MRI shadow in lung
Pet - 6.6mm Met in Upper R lobe
7/30 VAT surgery Mass General/Boston
8/24 port
8/30 - 4/28 Folfox. 12 rounds
2018
June CT shows new lung Mets.
July/Oct PETs...CLEAR!

User avatar
GrouseMan
Posts: 888
Joined: Mon Aug 12, 2013 12:30 pm
Location: SE Michigan USA

Re: Dandelion Root Extract

Postby GrouseMan » Mon Feb 18, 2019 9:35 am

No problem - you see I have an interest in medicinal uses of plants. Many drugs have come from the plant world and are effective treatments. So I don't discount the research out of hand. I have several books on the topic. Most indicate Dandelion root for Liver detox and as mention by another for Joint inflammation. It is a diuretic so be careful about dehydration.

Regards,

GrouseMan
DW 53 dx Jun 2013
CT mets Liver Spleen lung. IVb CEA~110
Jul 2013 Sig Resct
8/13 FolFox,Avastin 12Tx mild sfx, Ongoing 5-FU Avastin every 3 wks.
CEA: good marker
7/7/14 CT Can't see the spleen Mets.
8/16/15 CEA Up, CT new abdominal mets. Iri, 5-FU, Avastin every 2 wks.
1/16 Iri, Erbitux and likely Avastin (Trial) CEA going >.
1/17 CEA up again dropped from Trial, Mets growth 4-6 mm in abdomen
5/2/17 Failed second trial, Hospitalized 15 days 5/11. Home Hospice 5/26, at peace 6/4/2017

radnyc
Posts: 446
Joined: Tue Apr 06, 2010 6:32 pm

Re: Dandelion Root Extract

Postby radnyc » Mon Feb 18, 2019 11:31 am

From a reputable producer or better if you pick it yourself, dandelions and other plants and herbs can be useful in our cancer journeys. To rely 100% solely on your doctors’ opinions could be denying yourself of safe, natural alternatives. For thousands of years we’ve been healing ourselves with the earth’s medicinal gifts. My take is you can do both and benefit, science + nature. Do some homework.
DX Jan 2010, at age 47
Feb - colon resection - 2/17 nodes positive
April - liver mets - Stage 4
3 months Folfox chemotherapy
August '10 liver resection and HAI pump
7 months chemo FUDR HAI and Folfiri systemic
NED since August 2010
Last treatment April 2011
HAI Pump removed Dec 2015


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