I dug out some of the info (shown below) that I researched while undergoing FOLFOX. I did get permanent neuropathy in my feet, despite taking vitamins. My hands were pretty bad as well, but that went away in time, and they are fine. From reading other accounts, it seems to be the feet, are more impacted than the hands, but of course, it varies from person to person, and you may get neither.
The vitamins/minerals could be taken during chemo, but it's best to check with your dr beforehand, to make sure they don't interfere with chemo or any other medication. For example, I was told not to take vitamin c, because it could "weaken" the effect of the chemo.
The prescription meds don't prevent neuropathy, but can be prescribed to ease the symptoms. They can cause side effects, in some people.
During chemo I took alpha-lipoic acid, B vitamins, milk thistle and calcium, but I still got neuropathy, but who knows, maybe it would have been worse without. I just took them to make sure I was doing all I could.
After chemo, I tried gaberpentin, but I didn't realise it was something you had to take 3 times a day and gradually increase the dose. I didn't find it made a difference, so I stopped taking it after a few weeks.
Acetyl-L-carnitine (an amino acid)
B vitamins (B6, B12, B-complex)
Calcium and Magnesium
May 2015 right hemi CC cecum
removed terminal ileum, illeocecal valve, appendix, cecum, ascending colon, omentum
stage 3b T3 N1b MX 2/27 nodes (isolated tumour cells in 1 add'l node)
PNI - positive
LVI - positive
Folfox 12 sessions (without oxi for 11 & 12)
Neulasta with 3-12 due to low WBC count
CEA at diagnosis 8.6
CEA after surgery 1.2
CEA during chemo 4.6 / 3.3 / 2.3
CEA after chemo 1.5 / 1.2 / 1.2 /1.2 /1.2 / 1.4 / 1.1 / 1.2 / 1.9 / 1.3 / 1.6 /1.4 /1.5