A cure?

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radnyc
Posts: 446
Joined: Tue Apr 06, 2010 6:32 pm

A cure?

Postby radnyc » Mon Jan 28, 2019 7:45 pm

DX Jan 2010, at age 47
Feb - colon resection - 2/17 nodes positive
April - liver mets - Stage 4
3 months Folfox chemotherapy
August '10 liver resection and HAI pump
7 months chemo FUDR HAI and Folfiri systemic
NED since August 2010
Last treatment April 2011
HAI Pump removed Dec 2015

Nohogirl
Posts: 116
Joined: Sun Oct 14, 2018 12:15 am

Re: A cure?

Postby Nohogirl » Mon Jan 28, 2019 8:23 pm

I read this too today. Sounds very promising. Hoping if not this, a cure will be found soon.
04/18 DH 49 Stage 2A T3N0M0 rectal cancer moderately differentiated.
05/18 chemorad. (Xeloda) 28 days
08/18 Surgery- 24 cm, including entire rectum out
Path -Stage II T2N0M0 moderate to poorly diff. adenocarcinoma
0 of 15 lymph nodes
No PNI
No LVI
Clear margins
10/18-02/19 8 cycles of Folfox
02/19 Pet Scan. NED
08/19 Pet Scan NED
08/19 Colonoscopy Clear

mpbser
Posts: 953
Joined: Wed Apr 19, 2017 11:52 am

Re: A cure?

Postby mpbser » Mon Jan 28, 2019 8:46 pm

Thanks for sharing! Sounds VERY interesting!
Wife 4/17 Dx age 45
5/17 LAR
Adenocarcinoma
low grade
1st primary T3 N2b M1a
Stage IVA
8/17 Sub-total colectomy
2nd primary 5.5 cm T1 N0
9 of 96 nodes
CEA: < 2.9
MSS
Lynch no; KRAS wild
Immunohistochemsistry Normal
Fall 2017 FOLFOX shrank the 1 met in liver
1/18 Liver left hepatectomy seg 4
5/18 CT clear
12/18 MRI 1 liver met
3/7/19 Resection & HAI
4/1/19 Folfiri & FUDR
5/13/19 HAI pump catheter dislodge, nearly bled to death
6-7 '19 5FU 4 cycles
NED

rp1954
Posts: 1853
Joined: Mon Jun 13, 2011 1:13 am

Re: A cure?

Postby rp1954 » Tue Jan 29, 2019 2:17 am

It sounds promising and I definitely agree with the personalization and cocktail aspects. I hope that they yield drug cocktails that attack large masses quickly and thoroughly. I am a little concerned about the cost aspects, these things tend to be priced to new astronomical highs. As a practical matter, most of us may be stuck with older drugs and tests, first.

As an aside, substantial personalization information and cocktail recommendations were available in the Life Extension Foundation articles by 2002 that referenced articles on metronomic, cocktail, immune and immunochemo therapies. We did have to extend the LEF ranges on therapeutic levels for several items to maintain or restore cancer markers like CEA, CA199 and AFP for personalization. Experience does give us confidence in the personalization and cocktail approach.
watchful, active researcher and caregiver for stage IVb/c CC. surgeries 4/10 sigmoid etc & 5/11 para-aortic LN cluster; 8 yrs immuno-Chemo for mCRC; now no chemo
most of 2010 Life Extension recommendations and possibilities + more, some (much) higher, peaking ~2011-12, taper chemo to almost nothing mid 2018, IV C-->2021. Now supplements


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