panitumumab/vectibix question

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mpbser
Posts: 684
Joined: Wed Apr 19, 2017 11:52 am

panitumumab/vectibix question

Postby mpbser » Mon Jan 28, 2019 4:25 pm

For those of you who have had panitumumab/vectibix, was your tumor specimen tested for High expression levels of EGFR ligands epiregulin (EREG) and amphiregulin (AREG)? Would like to know because:

http://www.cancernetwork.com/colorectal ... vanced-crc
Wife 4/17 Dx age 45
5/17 - Lap left hemi
Adenocarcinoma
5 x 4 x 1 cm
low grade
T3 N2b M1a
Stage IV A
lymph nodes: 9 of 54
8/17 Sub-total colectomy
2nd tumor 5.5 cm T1 N0
CEA: 1.4, 2.1, 1.5, 1.9, 1.9, 2.1, 2.1, 2.4, 1.7, 2.0, 2.9, 2.2
MSS/MSI-L
Lynch no; KRAS wild
Immunohistochemsistry: Normal MLH1, MSH2, MSH6, and PMS2
Tumor DNA variants: MTOR, APC, TP53
1/18 Liver left hepatectomy seg 4
5/18 CT clear
12/18 MRI shows met
Resection & HAI Mar 7??

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