Hi. I decided to start a new thread since I needed some opinions and there doesn’t seem to be a specific thread for this topic. I am sure some others here may need or will be needing opinion on this as well.
Brief backgrounder: I am about to hit my 2 year mark on Keytruda monotherapy and have been NED for maybe a little more than a year (see sig below). Most experts recommend completing the 2 years of treatment if patients are responding, paralleling what was done in the clinical trials. But beyond that there isn’t much data on how to proceed with treatment. Some of the options I have heard are:
1) Stop treatments completely at 2 years and just monitor.
2) Continue dosing at the same dosage (200mg flat dose every 3 weeks)
3) Decreasing the dose to half (100mg) but still give it every 3 weeks.
4) Increase intervals in between doses by a week at a time until 6 weeks then maintain.
5) Stop treatments cold turkey then give a full dose every 3 months (the supposed length of Keytruda’s duration of action?).
For everyone here currently in the same boat or about to get there what are you and/or your oncs planning to do? I don’t mean to be insensitive to those who aren’t in the same situation. I am aware that it is a “good” problem to have. But for people like me for whom cost is a major issue it is something that has to be dealt with. Hoping people will chime in. Again hoping and praying for the best for all of us here still fighting.