weisssoccermom wrote:I was one of the lucky ones that had a complete clinical response. While I did not have the LAR afterwards ....instead I had a full thickness transanal excision.....I am 11+ years out from surgery (a little more than 12 from diagnosis). It is possible.
mozart13 wrote:depend's on the stage:
"Patients with stage II tumors had a higher complete response rate of 54 percent (23 of 43 patients) compared to 33 percent (87 of 265 patients) with clinical stage III tumors. Pathological complete response rates were in line with previous results from a multicenter study led by MSK and published in The Lancet, which ranged from 25 to 38 percent."
https://www.mskcc.org/clinical-updates/ ... alResearch
Talking here about Total Neoadjuvant Therapy.
Radiation peak is about 15-17 weeks,page 7/53:
http://www.iwwd.org/wp-content/uploads/ ... 015-NF.pdf
CF_69 wrote:That is a very interesting article.
I’m newly diagnosed myself. T3 N1 adenocarcinoma in the sigmoid right at the rectosigmoid junction. I believe I’m being treated as rectal since I am on Xeloda and getting radiation for 5 weeks.
I’m supposed to have surgery after and then possibly 4 months of chemo afterwards, depending on what they find.
I’m curious about this TNT idea. I will see what my onco thinks about it next time I see him.
A little about me, I’m 47 years old, male, no family history. The only symptom I had was occasional blood that got progressively worse, and in fact about 2-3 weeks before my colonoscopy the doctor sent me home with a dismissive tone and a tube of Preparation H.
I ate a fairly clean diet, worked out pretty regularly since high school. I definitely took several months off here and there over the years as I also have a bad back. I do have a weakness for Big Mac’s and I was a heavy beer drinker.
All scans looking for spread have come back clear. I’m in otherwise good health.
Anyway, not intending to turn this into my diary or anything. Just this article caught my attention so was a good spot to finally jump in to the water, so to speak.
weisssoccermom wrote:The first surgeon measured my tumor at 3 cm in however, he was way off. My tumor was actually located between 7 - 8 cm up and initially it had grown downwards which is why the first surgeon thought it was at 3 cm. Transanal is possible with tumors higher up (but there is a limit) particularly when the surgeon has access to the equipment for TEM (not to be confused with TME). TEM stands for transanal endoscopic microsurgery.
I have a question for your and your signature. It says T4N0M0 and you call that a stage 3a...however, stage 3 has some positive nodes. I recognize that the staging has changed somewhat but I just looked at the ACS and it still has all stage 3's having some form of lymph node involvement. Did the surgeon tell you this was your staging?
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