I am not MSI high, hence it was my understanding that, with MSS tumors, I would not be a good candidate for immunotherapy. I have, however, been recruited and approved for a trial at Mass General called nivolumab and ipilimumab and radiation therapy in mss and MSI high colorectal and pancreatic cancer (Ca209-806). Anyone participating? Any insight, information, wisdom or warnings to offer?
DX Aug. 2013 Resection 09/13.
08/14 CT : .7 CM pulmonary nodule--& multiple nodules.
03/15 15 dendritic cell vaccine-monthly
05/16 begin 3000 MG Xeloda & Avastin
2/2017: Port installed. Begin Folfiri and Avastin
8/2017: Xeloda, Avastin and Iranotican. 3-wk cycle.
2-6-18: small pulmonary embolim—some growth in one pulmonary tumor. Start Xarelto.
2-8-18 : Change of chemo: Xeloda with Oxaliplatin no avastin.
9/2018: Tumor growth. Begin Stivarga.