Same here. My husband is on maintenance chemo Xeloda plus Avastin ( Xeloda 10 days on, 10 days off and Avastin every 3 weeks) for two years. While his medical oncologist strongly insists on continuing this regimen to prevent recurrence (because of his extensive liver involvement with 12 lesions), his surgical oncologist ( his liver surgeon who, in my opinion, saved his life) thinks it's over treatment and wants him to stop.
Two years of accumulated Xeloda causes a lot of GI system discomfort and bloating, Avastin causes high blood pressure and high protein in the urine. Those side effects are definitely uncomfortable but they are somehow manageable and if this regimen prevents recurrence, my husband is more than willing to continue on.
We really don't know who to listen to between our two oncologists.
Wife to DH
09/2016: Dx at 50, CC Ascending colon, 10+ liver Mets
KRAS-Mut G12V, MSS, CEA 8
09/2016: Nearly blocked, Emergency colon surgery (LAR)
FOLFOXIRI+Avastin: 6 before and 6 after liver resection
01/2017: Liver resection, open, both lobes, 40% total liver cut, tumors either cut out or microwave ablation burn, all tumors are out
02/2017-01/2019 : Clean CT every 3-4 months, CEA between 2-3
06/2017-Present: Maintenance Chemo: Xeloda + Avastin