lymph node tested positive :(

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jep
Posts: 79
Joined: Sun Jun 11, 2017 7:45 pm

lymph node tested positive :(

Postby jep » Wed Oct 10, 2018 10:31 am

My husband finally got the results from his biopsy today . . . the lymph node tested positive for cancer :evil: . . . they want to do a PET scan to see if hopefully it's just this one node, and maybe it can be surgically removed . . . I don't know what else to say . . . my husband is so strong and just takes all of this in stride and I am not doing as well . . .
Husband DX Stage IV CC on May 16, 2017
47 years old
Tumor Location: recto-sigmoid
Tumor type: Adenocarcinoma
Tumor size: 7.4 cm
Tumor grade: G3
TNM code: T3N2M1
Positive lymph nodes: 8 out of 20
Baseline CEA value: .9
LVI: present
Perineural invasion: present
Surgical margins: clear (w/in microns)
Primary surgery type: LAR
Folfox (August 2017-January 2018)
Scope June '18 - CLEAR! - 2 polyps removed

jep
Posts: 79
Joined: Sun Jun 11, 2017 7:45 pm

Re: lymph node tested positive :(

Postby jep » Wed Oct 10, 2018 11:01 am

If you have any suggestions as to what we should ask the oncologist, please share them!
thank you everyone . . .
jep
Husband DX Stage IV CC on May 16, 2017
47 years old
Tumor Location: recto-sigmoid
Tumor type: Adenocarcinoma
Tumor size: 7.4 cm
Tumor grade: G3
TNM code: T3N2M1
Positive lymph nodes: 8 out of 20
Baseline CEA value: .9
LVI: present
Perineural invasion: present
Surgical margins: clear (w/in microns)
Primary surgery type: LAR
Folfox (August 2017-January 2018)
Scope June '18 - CLEAR! - 2 polyps removed

Achilles Torn
Posts: 105
Joined: Fri Dec 16, 2016 2:41 pm

Re: lymph node tested positive :(

Postby Achilles Torn » Wed Oct 10, 2018 1:31 pm

There is every reason to have hope for a positive outcome for your husband. Surgery still may be an option and if not, then systemic treatments may be very effective. There are several examples on this board of people with lymph node mets that have been going strong for many years and tolerating treatment well.

As for questions for the Onc....I would ask about complete genetic testing (if that hasn't been done). The more you know the better.

Hope that helps
AT
40 yo Male. BC Canada. Sigmoid Colectomy Dec. 2016
Pathology T3N2bM1 19 of 24 Nodes Positive + tumour deposits
PET scan - Para-Aortic and Iliac Lymph node spread. Stage VI.
Moderately differentiated. MSS. KRAS/BRAF Wild.
Mutations: TP53, ERBB4, MLL3, PDCD1LG2, PRKDC, SMAD3
FOLFOX Commenced Jan 9/2017 - Avastin(Bev) added after round 1.
June 2017 Dose Reduction on Round 11 due to Neuropathy.
Good PET Scan July 2017 - on maintenance 5FU/Bev every 2 weeks until progression.

jep
Posts: 79
Joined: Sun Jun 11, 2017 7:45 pm

Re: lymph node tested positive :(

Postby jep » Wed Oct 10, 2018 2:09 pm

Thank you AT . . . for both the optimism and the advice.
Husband DX Stage IV CC on May 16, 2017
47 years old
Tumor Location: recto-sigmoid
Tumor type: Adenocarcinoma
Tumor size: 7.4 cm
Tumor grade: G3
TNM code: T3N2M1
Positive lymph nodes: 8 out of 20
Baseline CEA value: .9
LVI: present
Perineural invasion: present
Surgical margins: clear (w/in microns)
Primary surgery type: LAR
Folfox (August 2017-January 2018)
Scope June '18 - CLEAR! - 2 polyps removed

rp1954
Posts: 1377
Joined: Mon Jun 13, 2011 1:13 am

Re: lymph node tested positive :(

Postby rp1954 » Fri Oct 12, 2018 12:46 am

oral chemo+supplemental chemistry asap, + 2nd surgery + later adding celecoxib (from ADAPT) is what we did.

I do suggest noting CEA, CA199, LDH as minimal markers for this approach if they are even "average" - e.g. CA199 over 12 or 22 and LDH over 170. We do something more like CBC and extended panels for chemistry e.g. you might ask for a CBC+Chem 25 or 26 and see what they offer. We just order them ourselves.

Slightly improved lab work can steer you better with ADAPT and other nicer chemistry.
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC


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