There are several aspects that should be considered. Specific proteo-glucans content are one aspect of strength and quality and the differences between PSK, PSP, and clones.
The bulk of the CRC, chemo and mushroom extract data that are available, are for PSK, the hot water extract of a particular Coriolus versicolor strain developed in Japan for cancer, from the 1960s. Most of the Coriolus extract on the market is alcohol extracted, more like a version developed in China for cancer around the 90s, called PSP. PSP clones are widely available and to varying degrees, (much more) inexpensive as alcohol extracts more stuff, more easily.
Sometime around the 90s, Life Extension Foundation started discussing the PSK-cancer literature, energetically, perhaps the most prominent voice on the internet and in print. Although LEF tried to give a brand neutral presentation, LEF did favor PSK strength and high quality as a cancer treatment aspect. LEF also sold the JHS Natural Coriolus Super Strength (CSS) at the best internet prices, once a year. JHS, a stickler for higher prices especially with ads, eventually fell into disagreement with LEF and ruptured LEF's internet sales of CSS ca 2014, as it has often done to internet sellers.
~10 years ago, there was some serious question about the relative cancer-survival performance between PSK-like and PSP-like extracts on the market, even same company. PSK was favored, but this difference might represent some particular CRC subgroup or condition, but that is unknown to me, beyond PSK success correlated with a peak CEA over 3. Our personal experience has been mostly with CSS; with some brief trials of PSP type materials.
For us, PSP yielded the highest WBC results, but at the expense of RBC and no advantage for platelets. We needed more platelets and RBC. Also highest WBC doesn't necessarily mean best WBC cancer immune performance, which is crucial in cancer. In general, some immune components can either kill or promote cancer cells, this is a pre-existing immune failure for many here on the day of diagnosis. The harder part is to test those immune properties and changes, well.
watchful, active caregiver for stage IVb CC since early 2010. immuno"Chemo forever," for mCRC