I replied to your PM but it is unopened.
There are a lot of lab studies that show various flavonoids reduce overexpression of ErbB2/HER2 in cancer cells and related pathways, or killing them, mostly for breast cancer. For over sixty years there has been been argumentation between ascorbate and flavonoids purists about vitamin C and cancer. My answer is well duh, use them all in their cheapest forms in sensitive cells.
In some papers, flavonoids and vitamin C are shown re-sensitizing CRC to 5FU, including real patients. Vitamin C is published as a KRAS/BRAF cell killer. In real life we found we needed 5FU-LV and Vitamin C + K2. We have been using various flavonoids since the beginning. I might advocate (at least) 1-2 of the highest strength cap for each
flavonoid you choose (can find or swallow), half dozen or more flavonoids. Perhaps 3-5 core flavonoids, like EGCG, quercetin, curcumin, silymarin, resveratrol, and 2-3 rotating ones, perhaps depending on supplies and availablity or even specials.
I think Dr. Lin's ADAPT work is important with some great results (e.g. stage IV patients starting ~20 years ago with median OS over 8 years), but needs more. We definitely didn't stop for addons to oral 5FU and celecoxib(Celebrex) rather padding out, carefully selecting and testing from the Life Extension lists of off label drugs and high potency supplements. Best of all about virtual (self) trials
, enrollment always seems to be open and treatments flexible, less argument with insurance (for low cost cash items, out of pocket anyway).