Phase 2 vs Phase 3 trials

[Steph20021]

What’s the difference between a phase 2 and a phase 3 trial? Also, is there a chance you get a placebo in either one?

Thanks for the help in advance.

[O Stoma Mia]

What’s the difference between a phase 2 and a phase 3 trial? Also, is there a chance you get a placebo in either one?

Thanks for the help in advance.

Here are the definitions of clinical trial phases

https://en.m.wikipedia.org/wiki/Phases_of_clinical_research

Whether or not you might get a placebo depends on the trial's research design. You have to look at the design page on that particular clinical trial's web page.

[Steph20021]

I just found this explanation of each phase which is pretty helpful!

http://www.cancer.ca/en/cancer-informat ... ?region=on

[Steph20021]

Thank you. I just re-read them. There’s two phase 3 trials in Toronto and participants are told whether they are getting the controlled standard treatment or the experimental one. That’s what I was hoping and expecting.

What’s the difference between a phase 2 and a phase 3 trial? Also, is there a chance you get a placebo in either one?

Thanks for the help in advance.

Here are the definitions of clinical trial phases

https://en.m.wikipedia.org/wiki/Phases_of_clinical_research

Whether or not you might get a placebo depends on the trial's research design. You have to look at the design page on that particular clinical trial's web page.

[SurvivorsSpouse]

In researching treatments for cancer, in patients under active treatment, there is no placebo arm. The studies are testing vs current line treatments. So, the treatment is either standard line treatment or with the study drug/protocol.

No one will tell a cancer patient that you risk receiving placebo rather than effective treatment.