Heart murmur...possible side effect folfiri avistin??

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teri3
Posts: 405
Joined: Fri Jan 09, 2015 11:03 am

Heart murmur...possible side effect folfiri avistin??

Postby teri3 » Tue Sep 04, 2018 9:12 pm

Last several times my oncologist has noticed an aortic heart murmur. I was wondering if this is a possible side effect from folfiri+avistin or am I just getting old lol? Anyone have this happen? She doesn't seem to concerned. But is talking possible further test.
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(

WarriorSpouse
Posts: 220
Joined: Tue Aug 16, 2016 9:02 pm

Re: Heart murmur...possible side effect folfiri avistin??

Postby WarriorSpouse » Tue Sep 04, 2018 11:19 pm

Interesting question. No experience on my wife's front, but I will share if something like this comes up. Please keep us posted and our thoughts are with you as you seek answers along the way. I hope you are feeling better soon.
WS
D/H 47 years old, 10/2014, Stage IV M/CRC, nodes 12/15, para-aortic, 5 cm sigmoid resection, positive Virchow. KRAS mut, MSS, Highly Differentiated, Lynch Neg, 5FU/LV and Avastin 1 YR (Oxi for 5 months), Zeloda/Bev since 01/2016. 02/2019 recurrence para-nodes, back to 5FU/LV Oxy/Bev. It is working again. "...Perseverance is not a long race; it is many short races one after the other."-Walter Elliot

teri3
Posts: 405
Joined: Fri Jan 09, 2015 11:03 am

Re: Heart murmur...possible side effect folfiri avistin??

Postby teri3 » Wed Sep 05, 2018 12:23 am

Thanks WS. I'll keep you posted and try to remember to ask my onc if she thinks it's a side effect, she's extremely upfront so I know she'll give me straight answers.
Teri
58 yrs old female
MSS KRAS mutation G12V
adenocarcinoma sigmoid colon dx 11-14
sigmoidectomy 11-14
Stage 3A
3 out of 20 lymph nodes involved
started FolFox 1-27-15
11 rounds FOLFOX last one 6-30-2015
7-29-2015 PET clear
5-14-2016 CT 2 nodules one in each lung
Confirmed pulmonary metastasis stage 4
FOLFIRi + Avistin started 8-16 11 rounds complete 12-16
CT 12-16 nodules shrunk chemo break wait and see :?
CT growth
VATS l lung 4 10 17
VATS r lung 4 24 17
CT 2 nodules r up and l low :(


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