MRI shows 6 new liver Mets 2 weeks after clean CT scan? CEA normal.

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mpbser
Posts: 474
Joined: Wed Apr 19, 2017 11:52 am

Re: MRI shows 6 new liver Mets 2 weeks after clean CT scan? CEA normal.

Postby mpbser » Tue Sep 18, 2018 7:18 am

Hope all went well yesterday.
Wife 4/17 Dx age 45
5/17 - Lap left hemi
Adenocarcinoma
5 x 4 x 1 cm
low grade
T3 N2b M1a
Stage IV A
lymph nodes: 9 of 54
8/17 Sub-total colectomy
2nd tumor 5.5 cm T1 N0
CEA: 1.4, 2.1, 1.5, 1.9, 1.9, 2.1, 2.1, 2.4, 1.7, 2.0
MSS/MSI-L
Lynch no; KRAS wild
Immunohistochemsistry: Normal MLH1, MSH2, MSH6, and PMS2
Tumor DNA variants: MTOR, APC, TP53
Liver left hepatectomy seg 4 1/31/18
5/18 NED

Cmac1275
Posts: 31
Joined: Mon Aug 06, 2018 4:21 pm

Re: MRI shows 6 new liver Mets 2 weeks after clean CT scan? CEA normal.

Postby Cmac1275 » Tue Sep 18, 2018 8:24 am

Thank you. Biopsy was a breeze. Hoping for good news when results come back.
42 yr, male, husband and father of 3
01/24/2018 — Dx with Stage IV Colon Cancer and liver mets
01/26/2018 — Partial colectomy. Two thirds colon removed
02/21/2018 — CEA @ 60
03/21/2018 — Began 6 rounds of FOLFOX / Avastin
06/21/2018 — CEA @ 4.7
07/02/2018 — Right hepatic lobectomy
08/28/2018 — MRI shows new spots on remaining ("old") liver)
09/04/2018 — PET scan shows new spots on both lobes
09/05/2018 — CEA @ 2.7

plastikos
Posts: 309
Joined: Wed Jan 14, 2015 6:09 am

Re: MRI shows 6 new liver Mets 2 weeks after clean CT scan? CEA normal.

Postby plastikos » Wed Sep 19, 2018 9:44 am

Been following this. Hoping the results turn out to be favorable. By the way, have you been tested for MSI status?
St. IV Colon CA @ 37, male, Kras wild, MSI-high (2014)
11/2014 Right Hemicolectomy + Liver Resection
12/2014 - 6/2015 FOLFOX + Cetuximab
10/2015 - Recurrence liver
Liver resection 10/2015
FOLFIRI 11/2015 - 5/2016
Recurrence liver, nodes 11/2016
Pembrolizumab started 12/2016 -> pseudoprogression(?) -> biliary obstruction -> biliary stenting
Chemo 4x: most mets inactive and smaller on PET-CT
March 2017 - Back on Pembrolizumab again
Sept 2017 - SIRT - > NED

Cmac1275
Posts: 31
Joined: Mon Aug 06, 2018 4:21 pm

Re: MRI shows 6 new liver Mets 2 weeks after clean CT scan? CEA normal.

Postby Cmac1275 » Wed Sep 19, 2018 8:28 pm

plastikos wrote:Been following this. Hoping the results turn out to be favorable. By the way, have you been tested for MSI status?



Thanks, Plastikos. Meeting with my new oncologist tomorrow. Will be asking to get more detail on exactly what they’ve tested for. If I’m being honest, when I was Dx’ed in January, I just plowed ahead with whatever the docs said to do. I suppose, in a way, that was a mechanism to avoid getting sucked into the inevitable phase of digging into every corner of the internet to find answers. Now that I’ve had this possible recurrence, that phase has officially arrived.
42 yr, male, husband and father of 3
01/24/2018 — Dx with Stage IV Colon Cancer and liver mets
01/26/2018 — Partial colectomy. Two thirds colon removed
02/21/2018 — CEA @ 60
03/21/2018 — Began 6 rounds of FOLFOX / Avastin
06/21/2018 — CEA @ 4.7
07/02/2018 — Right hepatic lobectomy
08/28/2018 — MRI shows new spots on remaining ("old") liver)
09/04/2018 — PET scan shows new spots on both lobes
09/05/2018 — CEA @ 2.7


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