Any body knows of Clinical trials for BRAF 600?

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Dionca
Posts: 48
Joined: Sat Dec 02, 2017 2:04 am

Re: Any body knows of Clinical trials for BRAF 600?

Postby Dionca » Wed Dec 26, 2018 9:08 pm

Wow, that's quite the Christmas present - a very impressive drop in CEA. That, combined with pain reduction and tumour shrinkage, sounds like you found the right trial. I'm very happy for you, and hope you continue to see good results.
stage 3b T3 N1b MX 2/27 nodes (surgery 4/2015)
moderately differentiated
PNI - positive
LVI - positive
Folfox 12 sessions (w/out oxi for 11 & 12)
Neulasta with 3-12 due to low WBC count
CEA at diagnosis 8.6
CEA after surgery 1.2
CEA during chemo 4.6 / 3.3 / 2.3
CEA after chemo 1.5 / 1.2 / 1.2 /1.2 /1.2 / 1.4 / 1.1 / 1.2 / 1.9 / 1.3 / 1.6 /1.4 /1.5
neuropathy
recurrence in left lung (surgery May 2020)

Steph20021
Posts: 553
Joined: Sat Dec 27, 2014 4:58 pm
Location: Ontario, Canada

Re: Any body knows of Clinical trials for BRAF 600?

Postby Steph20021 » Tue Jan 01, 2019 1:21 am

Thanks Dionca. The CT report is a bit underwhelming and only shows small shrinkage with the biggest shrinkage being about 1 cm off the side of my biggest rumour that used to cause pain. Nothing new and my chest is still clear. I also hope for continued results for a long time on this trial.
Dionca wrote:Wow, that's quite the Christmas present - a very impressive drop in CEA. That, combined with pain reduction and tumour shrinkage, sounds like you found the right trial. I'm very happy for you, and hope you continue to see good results.
DX 1/31/14 @ 33- SPS-T4a(invades visceral peri), N2a(6/106 LN), M1a(ovary) (Stage 4a) MSS; BRAF V600E
2/1/14-subtotal col, lost R ovary, temp ileo
3/14-9/14- folfox; sepsis
11/14-CT/PET: L ovary met, pelvic met, (?)ghost liver met(?)
12/14-folfiri -13 rds kept me stable from 3/15-6/15
8/15-HIPEC, NED
09/15- cea 0.9
05/16- recurrence in abdo wall and lymph nodes
01/17- pulmonary embolism
02/17- 1 wk radiation to abdo wall
08/16- on folfiri
01/18-folfox
11/18- Beacon trial-encorafenib & cetuximab


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