I'm once again at the crossroads and uncertain which way to go. Hopefully some of you have experience or suggestions!
My continuous low platelet counts caused me to sporadically get Folfox this past late winter into spring. With all the breaks, my CEA started climbing and is now 145. Scans show growth in lung mets and two new liver mets. In early August I started Stivarga and had to stop at day 11 due to extreme foot syndrome and rash. I contacted NIH but without the required platelet count of 100,000 (mine are continuously at 40s or low 50s), I don't qualify for any trials.
My hematologist wants a bone marrow bioposy (scheduled this week) to rule out issues there with platelet count, and we're fighting insurance which denied immune globulin infusions to boost count. So now I'm scheduled for splenectomy in beginning of September, but I'm not certain that's the right decision. With that big of surgery, I won't be getting any chemo until October (my last treatment of Folfox was May 23, then one week of Stivarga at only two pills a day).
Anyone been where I am right now? Should I try to ablate (if possible, have not had consult yet on that) liver tumors and do chemo with low platelets? My oncologist will give me if they don't drop any lower, and if we can get insurance to approve infusions to boost them, it's still a temporary fix. Or get splenectomy, which is major surgery and could fix platelet problem but no one knows for certain. I'm so confused!