Like you, after my first two cycles of FOLFOX I had to take two weeks off waiting for first my platelets then my WBC/neutrophils to rebound to treatable levels. Since then I've been getting a shot of Neulasta when my pump is disconnected, and expect to do so from now on. It has worked beautifully in keeping my WBC count and neutrophils up. I wish there was an equivalent for platelets!
It is important to take claritin daily to combat the histamines that can result--for me-- in severe throbbing pain in the back of the pelvis and breastbone. Even with claritin I've had to take ibuprofen a few times, but it isn't much of a problem. WIthout claritin--I failed to take it the first time--it was nasty.
F, 64 at DX CRC Stage IV (or "3 1/2" per Dana Farber consult, LOL)
3/17/18 blockage, emergency surgery, r hemicolectomy
11 of 25 nodes
5 of 5 mesentery nodes, matted
0.5 cm sub-capsular liver met removed
pT3 pN2b pM1
Neg CEA, neg BRAF, KRAS G12D, germline mut ATM
dMMR, MSI-H, Neg for Lynch
Added Neulasta 6/28/18
7/9/18 CT scans show no masses or enlarged nodes, 2mm indeterminate lung nodule
11/20/18 CT scans NED. Lung nodule likely calcified granuloma. Enlarged spleen.