Your situation sounds a lot like mine; we are the same age. I was already thin and have not yet managed to put much weight back on after surgery. Being in the hospital for a week on a liquid diet didn't do me any favors. I have trouble eating for a good 3-4 days after each infusion, even though I don't have any notable taste changes yet aside from first bite; I just have a lot of discomfort and bloating in my stomach that makes food seem unappetizing. It hasn't seemed bad enough to try Gas-X to address it but I think I will try that with my 3rd round if it isn't any better by then.
I also had cold sensitivity with the first round of Folfox, where even tap water was too cold for me, but it faded to where fridge-temperature was tolerable within a couple-few days. Freezer-temp sensitivity is lasting much longer for me after my second-round dose. I think this is pretty unique to the individual, so your experience may differ substantially.
The anti nausea meds for the infusion seem to vary based on the oncologist; they give me meds in pill form (zofran and compazine) about 30 minutes before my infusion starts, so I don't need to take them on my own beforehand. This is really just a preventative, since I haven't had any actual nausea yet. It sounds like some people here didn't get nausea meds until after they started to feel nausea, though.
Make sure you talk to your oncologist about being prone to nausea so they get you set up appropriately. If you haven't done that yet and you're not seeing the oncologist before the first infusion, call Monday or talk to the infusion nurse about it ASAP when you go in. They'll coordinate with the oncologist as needed. There should be plenty of time for them to make adjustments, as there will be a wait between checking in, blood work, getting the results, and the FOLFOX drugs being prepared. I am usually there a couple of hours minimum before they actually hook me up to an IV. Bring a book or some other way to occupy yourself.
I have been using nuun hydration tablets (the original formula, mostly because the combo packs of the new formula sold on Amazon include grape flavor and I hate grape, lol) to hydrate for a few days before, during and after my chemo treatment, and that is working well for me. Plus they taste a lot better than gatorade. I only get the hydration ones, not the ones with vitamins and not the ones with caffeine.
Based on the information gathered here, I'm also avoiding foods with added folate (e.g. I'm having oatmeal at breakfast rather than fortified cereal, using organic wheat bread for sandwiches, and checking all labels for added folate/folic acid). I can't tell you if that's helping or not, but it's an easy change to make so seems totally worth doing. I already was the kind of person who checked food labels to see what was in stuff.
I really would like to try the fasting thing too, which has been talked about on these boards, but it looks like all the studies that have looked at this have been with people who have a BMI higher than mine. As long as my side effects aren't too bad, I think it's probably best for me to keep eating as much as I can, so I don't lose any more weight.
DX: sigmoid colon cancer 5/2018. 48 F
laparoscopic sigmoid colon resection (24 cm removed); no stoma.
1 noncontiguous tumor deposit found and removed; margins clear
7.5cm X 6cm X 2cm adenocarcinoma -- G2 (moderately differentiated)
T3 pN1c M0
31 lymph nodes tested, 0 positive.
5/2018 before surgery, CEA 11.2
6/2018 began 12 infusions adjuvant FOLFOX; CEA 3.7
7/2018: CEA 1.9; 2nd infusion delayed because of neutropenia; Neulasta after all future infusions
9/2018: CEA 2.8 at infusion #6