boxhill wrote:Something odd: my CEA was 3 when I had surgery, but they said the tumor didn't express it so it is useless as a marker. This time I happened to get a printout of my full bloodwork results, and noticed that my CEA was 6. I don't know exactly what to make of it, since the cell-death theory of why chemo causes it to rise would not seem to apply here. Or maybe not. Thoughts?
boxhill wrote:After surgery they told me that my tumor "did not express CEA," so it would not work as a marker for me. That is what I meant by negative for CEA. I gather that this is the case for some percentage of people, perhaps around 30% or so for CRC. I think that the test is a cell staining. BTW, I also have a KRAS mutation. My understanding is that at this point it mostly affects treatment choices, as in EFGR-related therapies probably won't work.
Since then I've looked into it further. Here's an interesting article:
Now I wonder whether what they meant was that the cells were CEA lo. I'll have to ask my oncologist about it.
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