Hi Tina,
Just my 2 cents. The other week, I was having a constipation issue that was ultimately resolved with some Miralax and senna per my on-call doc at MSK. In a subsequent phone call, we went over steps I should take if constipation happens again, and I asked about enemas. The doctor said - no enemas during chemo. They don't want to take the risk of allowing any bacteria to enter via that route because it could cause an infection. If you decide it's something that you feel you should try, I would suggest checking with your doctor first.
Hope you get relief soon!
annieliz